CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-025778
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 MCG141011, isoform CRA_e 
Protein Synonyms/Alias
 MKIAA4213 protein 
Gene Name
 Ppp2r2a 
Gene Synonyms/Alias
 mKIAA4213; mCG_141011 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
124FQQEQENKIQSHSRGubiquitination[1]
167KIRWLPQKNAAQFLLubiquitination[1]
191WKISERDKRPEGYNLubiquitination[1]
329ALCDRHSKLFEEPEDubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
  
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 509 AA 
Protein Sequence
TPPSCRPLHP GRFLSAPVPV PSPLRCHPPP SAPSIPPSPG VGAEPRSRRP RRARQGHHLQ 60
RDMAGAGGGN DIQWCFSQVK GAVDDDVAEA DIISTVEFNH SGELLATGDK GGRVVIFQQE 120
QENKIQSHSR GEYNVYSTFQ SHEPEFDYLK SLEIEEKINK IRWLPQKNAA QFLLSTNDKT 180
IKLWKISERD KRPEGYNLKE EDGRYRDPTT VTTLRVPVFR PMDLMVEASP RRIFANAHTY 240
HINSISINSD YETYLSADDL RINLWHLEIT DRSFNIVDIK PANMEELTEV ITAAEFHPNS 300
CNTFVYSSSK GTIRLCDMRA SALCDRHSKL FEEPEDPSNR SFFSEIISSI SDVKFSHSGR 360
YMMTRDYLSV KIWDLNMENR PVETYQVHEY LRSKLCSLYE NDCIFDKFEC CWNGSDSVVM 420
TGSYNNFFRM FDRNTKRDIT LEASRENNKP RTVLKPRKVC ASGKRKKDEI SVDSLDFNKK 480
ILHTAWHPKE NIIAVATTNN LYIFQDKVN 509 
Gene Ontology
 GO:0000159; C:protein phosphatase type 2A complex; IEA:InterPro.
 GO:0008601; F:protein phosphatase type 2A regulator activity; IEA:InterPro.
 GO:0004722; F:protein serine/threonine phosphatase activity; IEA:Compara.
 GO:0006470; P:protein dephosphorylation; IEA:Compara.
 GO:0043278; P:response to morphine; IMP:MGI.
 GO:0007165; P:signal transduction; IEA:InterPro. 
Interpro
 IPR000009; PP2A_PR55.
 IPR018067; PP2A_PR55_CS.
 IPR015943; WD40/YVTN_repeat-like_dom.
 IPR001680; WD40_repeat.
 IPR017986; WD40_repeat_dom. 
Pfam
  
SMART
 SM00320; WD40 
PROSITE
 PS01024; PR55_1
 PS01025; PR55_2 
PRINTS
 PR00600; PP2APR55.