UniProt Accession

 B4DEG2_HUMAN; B4DEG2 

Genbank Protein ID

 AC132942; AK293610 

Genbank Nucleotide ID

 BAG57073.1 

Protein Name

 P2X purinoceptor 

Protein Synonyms/Alias

  

Gene Name

 P2RX5 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
88	VTAGNGVKTGRCLRR	ubiquitination	[1, 2, 3]
133	EDFTIFIKNHIRFPK	ubiquitination	[2, 3]
145	FPKFNFSKSNVMDVK	ubiquitination	[2, 3]
152	KSNVMDVKDRSFLKS	ubiquitination	[2, 3]
158	VKDRSFLKSCHFGPK	ubiquitination	[2, 3]
165	KSCHFGPKNHYCPIF	ubiquitination	[3]
227	RLDNKLSKSVSSGYN	ubiquitination	[2, 3]

Reference

 [1] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [3] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Ion channel; Ion transport; Receptor; Reference proteome; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 362 AA 

Protein Sequence

Gene Ontology

 GO:0016020; C:membrane; IEA:InterPro.
 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0005216; F:ion channel activity; IEA:InterPro.
 GO:0001614; F:purinergic nucleotide receptor activity; IEA:InterPro.
 GO:0035590; P:purinergic nucleotide receptor signaling pathway; IEA:GOC. 

Interpro

 IPR003048; P2X5_purnocptor.
 IPR027309; P2X_extracellular_dom.
 IPR001429; P2X_purnocptor. 

Pfam

 PF00864; P2X_receptor 

SMART

  

PROSITE

 PS01212; P2X_RECEPTOR 

PRINTS

 PR01312; P2X5RECEPTOR.
 PR01307; P2XRECEPTOR.