UniProt Accession

 METL5_HUMAN; Q9NRN9; D3DPC9; Q9NVX1 

Genbank Protein ID

 AF201938; AK001321; AC009967; CH471058; CH471058; BC093014; BC000921 

Genbank Nucleotide ID

 AAF86874.1; BAA91622.1; AAY14869.1; EAX11254.1; EAX11255.1; AAH93014.1; AAH00921.1 

Protein Name

 Methyltransferase-like protein 5 

Protein Synonyms/Alias

  

Gene Name

 METTL5 

Gene Synonyms/Alias

 DC3; HSPC133 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
21	QQVDGFEKPKLLLEQ	ubiquitination	[1, 2]
118	LLSNRMSKSFDTVIM	ubiquitination	[1]
132	MNPPFGTKNNKGTDM	ubiquitination	[1, 2]
143	GTDMAFLKTALEMAR	ubiquitination	[1]
191	YDLPASYKFHKKKSV	ubiquitination	[3]

Reference

 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661]
 [3] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473] 

Functional Description

 Probable methyltransferase (By similarity). 

Sequence Annotation

  

Keyword

 Complete proteome; Methyltransferase; Polymorphism; Reference proteome; Transferase. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 209 AA 

Protein Sequence

Gene Ontology

 GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
 GO:0003676; F:nucleic acid binding; IEA:InterPro. 

Interpro

 IPR002052; DNA_methylase_N6_adenine_CS.
 IPR007848; Small_mtfrase_dom. 

Pfam

 PF05175; MTS 

SMART

  

PROSITE

 PS00092; N6_MTASE 

PRINTS