UniProt Accession

 KAL1L_HUMAN; A0AUZ9; B7ZLN1; Q53TV8; Q53TW3; Q6IS05; Q8TCI1; Q96MI0; Q9UFC3 

Genbank Protein ID

 AK056911; AK074441; AC006994; AC007038; BC070141; BC126155; BC143914; AL133053 

Genbank Nucleotide ID

 BAB71308.1; BAB85085.1; AAY14880.1; AAX93088.1; AAH70141.1; AAI26156.1; AAI43915.1; CAB61379.1 

Protein Name

 KAT8 regulatory NSL complex subunit 1-like protein 

Protein Synonyms/Alias

 MSL1v2 

Gene Name

 KANSL1L 

Gene Synonyms/Alias

 C2orf67 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
108	LGEPSCNKLKNILYN	ubiquitination	[1]
110	EPSCNKLKNILYNGS	ubiquitination	[1]
165	TKDTNVDKVQLQNCK	ubiquitination	[1]
310	NKLWDDAKNGFARCT	ubiquitination	[1]
848	WSLWEQSKWHRRNSR	acetylation	[2, 3]
859	RNSRAYSKNVEGQDL	acetylation	[2, 3, 4, 5]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Lysine acetylation targets protein complexes and co-regulates major cellular functions.
 Choudhary C, Kumar C, Gnad F, Nielsen ML, Rehman M, Walther TC, Olsen JV, Mann M.
 Science. 2009 Aug 14;325(5942):834-40. [PMID: 19608861]
 [3] Proteomic investigations reveal a role for RNA processing factor THRAP3 in the DNA damage response.
 Beli P, Lukashchuk N, Wagner SA, Weinert BT, Olsen JV, Baskcomb L, Mann M, Jackson SP, Choudhary C.
 Mol Cell. 2012 Apr 27;46(2):212-25. [PMID: 22424773]
 [4] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377]
 [5] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 

Functional Description

  

Sequence Annotation

 MOD_RES 859 859 N6-acetyllysine.  

Keyword

 Acetylation; Alternative splicing; Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 987 AA 

Protein Sequence

Gene Ontology

 GO:0000123; C:histone acetyltransferase complex; IEA:InterPro. 

Interpro

 IPR026180; NSL1. 

Pfam

  

SMART

  

PROSITE

  

PRINTS