CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-032413
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Sorting nexin 13, isoform CRA_g 
Protein Synonyms/Alias
 Sorting nexin-13 
Gene Name
 SNX13 
Gene Synonyms/Alias
 hCG_2009798 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
149IQFATRSKEIDWQPYubiquitination[1]
331GDDINTIKNQINSLLubiquitination[2]
453YEQYLSEKASPRVTVubiquitination[1, 2, 3]
654RDFLEKRKKDLNAYLubiquitination[2]
655DFLEKRKKDLNAYLQubiquitination[2]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [3] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 888 AA 
Protein Sequence
MLTEASLSIW GWGSLGIVLF LITFGPFVIF YLTFYILCFV GGGLVVTLLF GKTNSEKYLE 60
QCEHSFLPPT SPGVPKCLEE MKREARTIKI DRRLTGANII DEPLQQVIQF SLRDYVQYWY 120
YTLSDDESFL LEIRQTLQNA LIQFATRSKE IDWQPYFTTR IVDDFGTHLR VFRKAQQKIT 180
EKDDQVKGTA EDLVDTFFEV EVEMEKEVCR DLVCTSPKDE EGFLRDLCEV LLYLLLPPGD 240
FQNKIMRYFV REILARGILL PLINQLSDPD YINQYVIWMI RDSNCNYEAF MNIIKLSDNI 300
GELEAVRDKA AEELQYLRSL DTAGDDINTI KNQINSLLFV KKVCDSRIQR LQSGKEINTV 360
KLAANFGKLC TVPLDSILVD NVALQFFMDY MQQTGGQAHL FFWMTVEGYR VTAQQQLEVL 420
LSRQRDGKHQ TNQTKGLLRA AAVGIYEQYL SEKASPRVTV DDYLVAKLAD TLNHEDPTPE 480
IFDDIQRKVY ELMLRDERFY PSFRQNALYV RMLAELDMLK DPSFRGSDDG DGESFNGSPT 540
GSINLSLDDL SNVSSDDSVQ LHAYISDTVY ADYDPYAVAG VCNDHGKTYA LYAITVHRRN 600
LNSEEMWKTY RRYSDFHDFH MRITEQFESL SSILKLPGKK TFNNMDRDFL EKRKKDLNAY 660
LQLLLAPEMM KASPALAHYV YDFLENKAYS KGKGDFARKM DTFVNPLRNS MRNVSNAVKS 720
LPDSLAEGMT KMSDNMGKMS ERLGQDIKQS FFKVPPLIPK TDSDPEHRRV SAQLDDNVDD 780
NIPLRVMLLL MDEVFDLKER NQWLRRNIKN LLQQLIRATY GDTINRKIVD HVDWMTSPEQ 840
VADSVKRFRD AFWPNGILAE AVPCRDKSIR MRTRVAGKTK LLAIMPGE 888 
Gene Ontology
 GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
 GO:0007154; P:cell communication; IEA:InterPro.
 GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro. 
Interpro
 IPR001683; Phox.
 IPR003114; Phox_assoc.
 IPR013996; PX_assoc_Snx13.
 IPR000342; Regulat_G_prot_signal.
 IPR016137; Regulat_G_prot_signal_superfam.
 IPR013937; Sorting_nexin_C. 
Pfam
 PF08628; Nexin_C
 PF00787; PX
 PF02194; PXA
 PF00615; RGS 
SMART
 SM00312; PX
 SM00313; PXA
 SM00315; RGS 
PROSITE
 PS50195; PX
 PS51207; PXA
 PS50132; RGS 
PRINTS