CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-006912
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Iron transporter FTH1 
Protein Synonyms/Alias
  
Gene Name
 FTH1 
Gene Synonyms/Alias
 YBR207W; YBR1446 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
211LASIIYSKDNNLLGNubiquitination[1]
219DNNLLGNKTQKGVKFubiquitination[1]
450PDSQRRSKDSSVPLIubiquitination[1]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301] 
Functional Description
 High affinity iron transporter probably involved in transport of intravacuolar stores of iron. 
Sequence Annotation
 MOD_RES 449 449 Phosphoserine.
 MOD_RES 453 453 Phosphoserine.  
Keyword
 Complete proteome; Ion transport; Iron; Iron transport; Membrane; Phosphoprotein; Reference proteome; Transmembrane; Transmembrane helix; Transport; Vacuole. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 465 AA 
Protein Sequence
MAFEDYFSFQ IFFIFLRESL EIVVIVSILL TIVKQGLSVE DDSPFEGSSS SAGLPSPNTN 60
TNADSTTAFL QAGPSDGNAI GTSATAANNK SRPLNVEEEE EIYEYSNELR DQDRESDEHT 120
ADNVKLYQKL KIQILAGGAF GLLLCMLIGG AFVSIFYHIG TDLWTLSEHY YEGVLSLVAS 180
VIISVMGLFF LRMGKLREKF RVKLASIIYS KDNNLLGNKT QKGVKFSEKY SFFILPFITT 240
LREGLEAVVF IGGIGIDQPL SSIPLSMVLA TAISTVFGIF FFRYSSSLSL KICLVVATCF 300
LYLIAAGLFS KGVWQLELQD YVNKCNGQDM SEVGNGPGSY DISRSVWHVN CCNGEKDGGW 360
MIFTAIFGWT NSATVGSVIS YNAYWLVLIC ALKLLMIEEK YGYIPYLPIS WQKKRIMKRL 420
SIAKASLDLK HHTSELNSST SEPDSQRRSK DSSVPLIIDS SGSAN 465 
Gene Ontology
 GO:0000329; C:fungal-type vacuole membrane; IDA:SGD.
 GO:0016021; C:integral to membrane; ISM:SGD.
 GO:0005381; F:iron ion transmembrane transporter activity; TAS:SGD.
 GO:0006897; P:endocytosis; IMP:SGD.
 GO:0006827; P:high-affinity iron ion transport; IPI:SGD.
 GO:0055072; P:iron ion homeostasis; IEA:UniProtKB-KW. 
Interpro
 IPR004923; FTR1. 
Pfam
 PF03239; FTR1 
SMART
  
PROSITE
  
PRINTS