CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-037261
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 E3 ubiquitin-protein ligase RNF19B 
Protein Synonyms/Alias
  
Gene Name
 RNF19B 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
187ADPPLMHKYEEFMLRubiquitination[1]
267QTLRVRTKHTSGLSYubiquitination[1]
337SGCTFWGKKPWSRKKubiquitination[2]
338GCTFWGKKPWSRKKKubiquitination[2]
453GVSTANGKGVKIEFDubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Metal-binding; Reference proteome; Repeat; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 587 AA 
Protein Sequence
MGSEKDSESP RSTSLHAAAP DPKCRSGGRR RRLTLHSVFS ASARGRRARA KPQAEPPPPA 60
AQPPPAPAPA AAQGPPPEAL PAEPAAEAEA EAAAAAAEPG FDDEEAAEGG GPGAEEVECP 120
LCLVRLPPER APRLLSCPHR SCRDCLRHYL RLEISESRVP ISCPECSERL NPHDIRLLLA 180
DPPLMHKYEE FMLRRYLASD PDCRWCPAPD CGYAVIAYGC ASCPKLTCER EGCQTEFCYH 240
CKQIWHPNQT CDMARQQRAQ TLRVRTKHTS GLSYGQESGP DDIKPCPRCS AYIIKMNDGS 300
CNHMTCAVCG CEFCWLCMKE ISDLHYLSPS GCTFWGKKPW SRKKKILWQL GTLIGAPVGI 360
SLIAGIAIPA MVIGIPVYVG RKIHSRYEGR KTSKHKRNLA ITGGVTLSVI ASPVIAAVSV 420
GIGVPIMLAY VYGVVPISLC RGGGCGVSTA NGKGVKIEFD EDDGPITVAD AWRALKNPSI 480
GESSIEGLTS VLSTSGSPTD GLSVMQGPYS ETASFAALSG GTLSGGILSS GKGKYSRLEV 540
QADVQKEIFP KDTASLGAIS DNASTRAMAG SIISSYNPQD RFSMIHA 587 
Gene Ontology
 GO:0008270; F:zinc ion binding; IEA:InterPro. 
Interpro
 IPR002867; Znf_C6HC.
 IPR001841; Znf_RING.
 IPR013083; Znf_RING/FYVE/PHD. 
Pfam
 PF01485; IBR 
SMART
 SM00647; IBR
 SM00184; RING 
PROSITE
 PS50089; ZF_RING_2 
PRINTS