CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-021896
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Anaerobic ribonucleoside-triphosphate reductase 
Protein Synonyms/Alias
  
Gene Name
 nrdD 
Gene Synonyms/Alias
 STM4452 
Created Date
 July 27, 2013 
Organism
 Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) 
NCBI Taxa ID
 99287 
Lysine Modification
Position
Peptide
Type
References
320NRIAGLGKNRKTAVFacetylation[1]
Reference
 [1] Regulation of cellular metabolism by protein lysine acetylation.
 Zhao S, Xu W, Jiang W, Yu W, Lin Y, Zhang T, Yao J, Zhou L, Zeng Y, Li H, Li Y, Shi J, An W, Hancock SM, He F, Qin L, Chin J, Yang P, Chen X, Lei Q, Xiong Y, Guan KL.
 Science. 2010 Feb 19;327(5968):1000-4. [PMID: 20167786] 
Functional Description
  
Sequence Annotation
 DOMAIN 3 92 ATP-cone.
 DOMAIN 583 708 Glycine radical.
 MOD_RES 681 681 Glycine radical (By similarity).  
Keyword
 ATP-binding; Complete proteome; Nucleotide-binding; Organic radical; Oxidoreductase; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 712 AA 
Protein Sequence
MTPHVMKRDG CKVPFKSERI KEAILRAAKA AGVDDADYCA TVAEVVSSQM NARSQVDINE 60
IQTAVENQLM SGPYKQLARA YIEYRHDRDI QREKRGRLNQ EIRGLVEQTN SALLNENANK 120
DSKVIPTQRD LLAGIVAKHY ARQHLLPRDV VQAHERGDIH YHDLDYSPFF PMFNCMLIDL 180
KGMLTQGFKM GNAEIEPPKS ISTATAVTAQ IIAQVASHIY GGTTINRIDE VLAPFVTESY 240
NKHRKTADEW QIPDAEGYAR SRTEKECYDA FQSLEYEVNT LHTANGQTPF VTFGFGLGTS 300
WESRLIQASI LRNRIAGLGK NRKTAVFPKL VFAIRDGLNH KFGDPNYDIK QLALECASKR 360
MYPDILNYDQ VVKVTGSFKT PMGCRSFLGV WENENGEQIH DGRNNLGVIS LNLPRIALEA 420
KGDETAFWKL LDERLALARK ALMTRIARLE GVKARVAPIL YMEGACGVRL KADDDVSEIF 480
KNGRASISLG YIGIHETINA LFGGEHLYDS EQLRAKGIAI VERLRQAVDQ WKDETGYGFS 540
LYSTPSENLC DRFCRLDTAE FGVVPGVTDK GYYTNSFHLD VEKKVNPYDK IDFEAPYPPL 600
ANGGFICYGE YPNIQHNLKA LEDVWDYSYQ HVPYYGTNTP IDECYECGFT GEFECTSKGF 660
TCPKCGNHDA ARVSVTRRVC GYLGSPDARP FNAGKQEEVK RRVKHLGNGQ IG 712 
Gene Ontology
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0008998; F:ribonucleoside-triphosphate reductase activity; IEA:EC.
 GO:0006260; P:DNA replication; IEA:InterPro. 
Interpro
 IPR005144; ATP-cone.
 IPR019777; Form_AcTrfase_GR_CS.
 IPR001150; Gly_radical.
 IPR012833; NrdD. 
Pfam
 PF03477; ATP-cone 
SMART
  
PROSITE
 PS51161; ATP_CONE
 PS00850; GLY_RADICAL_1
 PS51149; GLY_RADICAL_2 
PRINTS