CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-012938
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 KAT8 regulatory NSL complex subunit 3 
Protein Synonyms/Alias
 NSL complex protein NSL3; Non-specific lethal 3 homolog 
Gene Name
 Kansl3 
Gene Synonyms/Alias
 Nsl3 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
613SSPLPGAKPSKRPKIacetylation[1]
795LAATPGGKPTAIHQLacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
 As part of the NSL complex it is involved in acetylation of nucleosomal histone H4 on several lysine residues and therefore may be involved in the regulation of transcription (By similarity). 
Sequence Annotation
 MOD_RES 523 523 Phosphoserine (By similarity).
 MOD_RES 540 540 Phosphoserine (By similarity).  
Keyword
 Chromatin regulator; Complete proteome; Nucleus; Phosphoprotein; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 877 AA 
Protein Sequence
MAHRGGERDF QTSARRMGTS LLFQLSVHER ELDLVFLDHS YAKPWSAHPD ASSARPTRML 60
FVTPRRQQEN TIESDVPIDV ETVTATPAPL YDNQKARSVM NECERHVIFA RTDADAPPPP 120
EDWEEHVNRT GWTVAQNKLF NKILKALQSD RLARLANEGA CNEPVLRRVA VDKCARRVRQ 180
ALASVSWDTK LIQWLHTTLV ETLSLPMLAA YLDALQTLKG KIPTLIDRML VSSNTKTGAA 240
GAEALSLLLK RPWDPAVGVL SHNKPSKLPG SPLILIASSG PSSSVFPASR RHRFWQSQLS 300
CLGKVIPVAT HLLNNGSGVG VLQCLEHMTG AVRSKVLEIH SHFPHKPIIL IGWSTGALVA 360
CHVSVMEYVT AVVCLGFPLL TVDGPRGDVD DPLLDMKTPV LFVIGQNSLQ CHPEAMEDFR 420
EKIRAENSLV VVGGADDNLR ISKAKKKSEG LTQSMVDRCI QDEIVDFLTG VLTRAEGHVG 480
SEPRDQDAEK KKKPRDVARR DLAFEIPERG SRPASPAARL PTSPSGSEDL SSVSSSPTSS 540
PKTKGTTVTS AQKSSQIGTS QLLRRHVQRT DAVLTHRQAQ VPISSEPVEE VEKEELRVQL 600
KRHHPSSPLP GAKPSKRPKI KVSLISQGDT VGGPCTLSQG GTPEAAGGKP ITMTLGASAG 660
AKELTGLLTT AKSSSSEGGV TASAAPSVAS SNATPNAIHT LQSRLVATSP GSSLPGAASA 720
SSLLQGLSFS LQDISSKTTG LPGSPSPGPA PQATSVKLPT PMQSLGAITT GTSTIVRTIP 780
VATTLSSLAA TPGGKPTAIH QLLTNGGLAK LASSLPGLAQ ISNQASGLKV PTTITLTLRG 840
QPSRITTLSP MGSGAAASEE PNSQMLPSSS QRLPPAP 877 
Gene Ontology
 GO:0000123; C:histone acetyltransferase complex; ISS:UniProtKB.
 GO:0046972; F:histone acetyltransferase activity (H4-K16 specific); IEA:Compara.
 GO:0043995; F:histone acetyltransferase activity (H4-K5 specific); IEA:Compara.
 GO:0043996; F:histone acetyltransferase activity (H4-K8 specific); IEA:Compara.
 GO:0043984; P:histone H4-K16 acetylation; ISS:UniProtKB.
 GO:0043981; P:histone H4-K5 acetylation; ISS:UniProtKB.
 GO:0043982; P:histone H4-K8 acetylation; ISS:UniProtKB. 
Interpro
 IPR026555; NSL3/Tex30. 
Pfam
  
SMART
  
PROSITE
  
PRINTS