CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-016811
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Nuclear pore complex protein Nup88 
Protein Synonyms/Alias
 88 kDa nucleoporin; Nucleoporin Nup88 
Gene Name
 Nup88 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
228EESLILNKGRAYTASubiquitination[1]
598EEIQRRVKLLCDQKRacetylation[2]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337] 
Functional Description
 Essential component of nuclear pore complex (By similarity). 
Sequence Annotation
 MOD_RES 35 35 Phosphoserine (By similarity).
 MOD_RES 518 518 Phosphoserine (By similarity).
 MOD_RES 526 526 Phosphothreonine (By similarity).
 MOD_RES 541 541 Phosphoserine (By similarity).  
Keyword
 Alternative splicing; Coiled coil; Complete proteome; mRNA transport; Nuclear pore complex; Nucleus; Phosphoprotein; Protein transport; Reference proteome; Translocation; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 753 AA 
Protein Sequence
MAAAVGPLGD GELWQSWLPN HVVFLRLREG VRNQSPAEAE KPAASTSPSC PSLPPHLPTR 60
NLVFGLGGEL FLWDAEGSAF LVVRLRGPSG GGVEPPLSQY QRLLCINPPL FEIHQVLLSP 120
TQHHVALIGS KGLMALELPQ RWGKDSEFEG GKATVNCSTI PIAERFFTSS TSLTLKHAAW 180
YPSEMLDPHI VLLTSDNVIR IYSLREPQTP TKVIVLSEAE EESLILNKGR AYTASLGETA 240
VAFDFGPLVT VSKNIFEQKD RDVVAYPLYI LYENGETFLT YVSLLHSPGN IGKLLGPLPM 300
HPAAEDNYGY DACAILCLPC VPNILVIATE SGMLYHCVVL EGEEEDDQTL EKSWDPRADF 360
IPSLYVFECV ELELALKLAS GEDDPFASDF SCPIKLHRDP KCPSRYHCSH EAGVHSVGLT 420
WIHKLHKFLG SDEEDKDSLQ ELTAEQKCFV EHILCTKPLP CRQPAPIRGF WIVPDILGPT 480
MICITSTYEC LIRPLLSTVH PASPPLLCTQ EDAEVAESPL RILAETPDSF EKHIKRILQR 540
SAANPAFLKN CSARSSEKDL APPPEECLQL ISRATQVFRE QYILKQDLAK EEIQRRVKLL 600
CDQKRKQLED LNYCREERVS HLFRKSLREM AERLADKYEE AKEKQEDIMN RMKKVLHSFH 660
AQLPVLSDSE RDMKKELQLI PDQLRHLGNA IKQVTMKKDY QQRKMEKVLS PQKPTITLSA 720
YQRKCIQSIL KEEGEHIREM VKQINDIRNH VTF 753 
Gene Ontology
 GO:0005643; C:nuclear pore; IEA:UniProtKB-SubCell.
 GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
 GO:0015031; P:protein transport; IEA:UniProtKB-KW. 
Interpro
 IPR019321; Nucleoporin_Nup88. 
Pfam
 PF10168; Nup88 
SMART
  
PROSITE
  
PRINTS