CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-014539
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Vesicle-associated membrane protein 1 
Protein Synonyms/Alias
 VAMP-1; Synaptobrevin-1 
Gene Name
 Vamp1 
Gene Synonyms/Alias
 Syb1 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
61KVLERDQKLSELDDRubiquitination[1]
Reference
 [1] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113
Functional Description
 Involved in the targeting and/or fusion of transport vesicles to their target membrane. 
Sequence Annotation
 DOMAIN 33 93 v-SNARE coiled-coil homology.
 MOD_RES 63 63 Phosphoserine (By similarity).  
Keyword
 Alternative splicing; Cell junction; Coiled coil; Complete proteome; Cytoplasmic vesicle; Membrane; Mitochondrion; Mitochondrion outer membrane; Phosphoprotein; Reference proteome; Synapse; Synaptosome; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 118 AA 
Protein Sequence
MSAPAQPPAE GTEGAAPGGG PPGPPPNTTS NRRLQQTQAQ VEEVVDIMRV NVDKVLERDQ 60
KLSELDDRAD ALQAGASVFE SSAAKLKRKY WWKNCKMMIM LGAICAIIVV VIVIYIFT 118 
Gene Ontology
 GO:0030054; C:cell junction; IEA:UniProtKB-KW.
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
 GO:0043005; C:neuron projection; IEA:UniProtKB-SubCell.
 GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell.
 GO:0006886; P:intracellular protein transport; TAS:RGD.
 GO:0016192; P:vesicle-mediated transport; TAS:RGD. 
Interpro
 IPR001388; Synaptobrevin.
 IPR016444; Synaptobrevin_met/fun. 
Pfam
 PF00957; Synaptobrevin 
SMART
  
PROSITE
 PS00417; SYNAPTOBREVIN
 PS50892; V_SNARE 
PRINTS
 PR00219; SYNAPTOBREVN.