CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-005410
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 2-octaprenyl-6-methoxyphenol hydroxylase 
Protein Synonyms/Alias
  
Gene Name
 ubiH 
Gene Synonyms/Alias
 visB; b2907; JW2875 
Created Date
 July 27, 2013 
Organism
 Escherichia coli (strain K12) 
NCBI Taxa ID
 83333 
Lysine Modification
Position
Peptide
Type
References
241VLSWSDEKFCRELQSacetylation[1]
Reference
 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618
Functional Description
 Oxygenase that introduces the hydroxyl group at carbon four of 2-octaprenyl-6-methoxyphenol resulting in the formation of 2-octaprenyl-6-methoxy-1,4-benzoquinone. 
Sequence Annotation
  
Keyword
 Complete proteome; FAD; Flavoprotein; Monooxygenase; Oxidoreductase; Reference proteome; Ubiquinone biosynthesis. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 392 AA 
Protein Sequence
MSVIIVGGGM AGATLALAIS RLSHGALPVH LIEATAPESH AHPGFDGRAI ALAAGTCQQL 60
ARIGVWQSLA DCATAITTVH VSDRGHAGFV TLAAEDYQLA ALGQVVELHN VGQRLFALLR 120
KAPGVTLHCP DRVANVARTQ SHVEVTLESG ETLTGRVLVA ADGTHSALAT ACGVDWQQEP 180
YEQLAVIANV ATSVAHEGRA FERFTQHGPL AMLPMSDGRC SLVWCHPLER REEVLSWSDE 240
KFCRELQSAF GWRLGKITHA GKRSAYPLAL THAARSITHR TVLVGNAAQT LHPIAGQGFN 300
LGMRDVMSLA ETLTQAQERG EDMGDYGVLC RYQQRRQSDR EATIGVTDSL VHLFANRWAP 360
LVVGRNIGLM TMELFTPARD VLAQRTLGWV AR 392 
Gene Ontology
 GO:0008681; F:2-octaprenyl-6-methoxyphenol hydroxylase activity; IMP:EcoCyc.
 GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
 GO:0016709; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen; IEA:InterPro.
 GO:0009416; P:response to light stimulus; IMP:EcoliWiki.
 GO:0006979; P:response to oxidative stress; IMP:EcoliWiki.
 GO:0006744; P:ubiquinone biosynthetic process; IMP:EcoCyc. 
Interpro
 IPR002938; mOase_FAD-bd.
 IPR003042; Rng_hydrolase-like.
 IPR018168; Ubi_Hdrlase_CS.
 IPR010971; Ubi_Hdrxlases.
 IPR011295; UbiH. 
Pfam
 PF01494; FAD_binding_3 
SMART
  
PROSITE
 PS01304; UBIH 
PRINTS
 PR00420; RNGMNOXGNASE.