CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-002388
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 GTP-binding protein RHO2 
Protein Synonyms/Alias
  
Gene Name
 RHO2 
Gene Synonyms/Alias
 YNL090W; N2237 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
130LRQEAHFKENATDEMubiquitination[1]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, VillĂ©n J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301
Functional Description
  
Sequence Annotation
 NP_BIND 14 21 GTP (By similarity).
 NP_BIND 61 65 GTP (By similarity).
 NP_BIND 119 122 GTP (By similarity).
 MOTIF 36 44 Effector region (By similarity).
 MOD_RES 189 189 Cysteine methyl ester (By similarity).
 LIPID 188 188 S-palmitoyl cysteine (Probable).
 LIPID 189 189 S-geranylgeranyl cysteine (By  
Keyword
 Cell membrane; Complete proteome; GTP-binding; Lipoprotein; Membrane; Methylation; Nucleotide-binding; Palmitate; Prenylation; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 192 AA 
Protein Sequence
MSEKAVRRKL VIIGDGACGK TSLLYVFTLG KFPEQYHPTV FENYVTDCRV DGIKVSLTLW 60
DTAGQEEYER LRPFSYSKAD IILIGFAVDN FESLINARTK WADEALRYCP DAPIVLVGLK 120
KDLRQEAHFK ENATDEMVPI EDAKQVARAI GAKKYMECSA LTGEGVDDVF EVATRTSLLM 180
KKEPGANCCI IL 192 
Gene Ontology
 GO:0005622; C:intracellular; IEA:InterPro.
 GO:0016020; C:membrane; IDA:SGD.
 GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
 GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
 GO:0003924; F:GTPase activity; IDA:SGD.
 GO:0007015; P:actin filament organization; TAS:SGD.
 GO:0030010; P:establishment of cell polarity; TAS:SGD.
 GO:0031505; P:fungal-type cell wall organization; TAS:SGD.
 GO:0007017; P:microtubule-based process; TAS:SGD.
 GO:0007264; P:small GTPase mediated signal transduction; TAS:SGD. 
Interpro
 IPR027417; P-loop_NTPase.
 IPR005225; Small_GTP-bd_dom.
 IPR001806; Small_GTPase.
 IPR003578; Small_GTPase_Rho. 
Pfam
 PF00071; Ras 
SMART
 SM00174; RHO 
PROSITE
 PS51420; RHO 
PRINTS
 PR00449; RASTRNSFRMNG.