UniProt Accession

 NDUA8_PONAB; P0CB91; Q5RA56 

Genbank Protein ID

 CR859165 

Genbank Nucleotide ID

 CAH91354.1 

Protein Name

 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 

Protein Synonyms/Alias

 Complex I-19kD; CI-19kD; NADH-ubiquinone oxidoreductase 19 kDa subunit 

Gene Name

 NDUFA8 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) 

NCBI Taxa ID

 9601 

Lysine Modification

Position	Peptide	Type	References
19	ELKVDEVKISSAVLK	ubiquitination	[1]
65	EEGKLVNKCALDFFR	ubiquitination	[1]

Reference

 [1] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789] 

Functional Description

 Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). 

Sequence Annotation

 DOMAIN 29 69 CHCH 1.
 DOMAIN 71 113 CHCH 2.
 MOTIF 36 46 C-X9-C motif 1.
 MOTIF 56 66 C-X9-C motif 2.
 MOTIF 78 88 C-X9-C motif 3.
 MOTIF 100 110 C-X9-C motif 4.
 DISULFID 36 66 Potential.
 DISULFID 46 56 Potential.
 DISULFID 78 110 Potential.
 DISULFID 88 100 Potential.  

Keyword

 Complete proteome; Disulfide bond; Electron transport; Mitochondrion; Reference proteome; Repeat; Respiratory chain; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 172 AA 

Protein Sequence

Gene Ontology

 GO:0005758; C:mitochondrial intermembrane space; IEA:UniProtKB-SubCell.
 GO:0070469; C:respiratory chain; IEA:UniProtKB-KW.
 GO:0022900; P:electron transport chain; IEA:UniProtKB-KW. 

Interpro

 IPR010625; CHCH.
 IPR016680; NADH_Ub_cplx-1_asu_su-8. 

Pfam

 PF06747; CHCH 

SMART

  

PROSITE

  

PRINTS