| Tag | Content |
|---|
| CPLM ID | CPLM-006319 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Phosphoglucomutase-1 |
Protein Synonyms/Alias | PGM 1; Glucose phosphomutase 1 |
Gene Name | PGM1 |
Gene Synonyms/Alias | YKL127W |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 179 | NKLGKNQKYGPLLVD | acetylation | [1] | | 507 | VKFSNGTKFVLRLSG | acetylation | [1] |
|
Reference | [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae. Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C. Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [ PMID: 22865919] |
Functional Description | This enzyme participates in both the breakdown and synthesis of glucose. Can also act on mannose. |
Sequence Annotation | ACT_SITE 120 120 Phosphoserine intermediate (By
METAL 120 120 Magnesium; via phosphate group (By
METAL 291 291 Magnesium (By similarity).
METAL 293 293 Magnesium (By similarity).
METAL 295 295 Magnesium (By similarity).
MOD_RES 120 120 Phosphoserine. |
Keyword | Carbohydrate metabolism; Complete proteome; Cytoplasm; Glucose metabolism; Isomerase; Magnesium; Metal-binding; Phosphoprotein; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 570 AA |
Protein Sequence | MSLLIDSVPT VAYKDQKPGT SGLRKKTKVF MDEPHYTENF IQATMQSIPN GSEGTTLVVG 60
GDGRFYNDVI MNKIAAVGAA NGVRKLVIGQ GGLLSTPAAS HIIRTYEEKC TGGGIILTAS 120
HNPGGPENDL GIKYNLPNGG PAPESVTNAI WEASKKLTHY KIIKNFPKLN LNKLGKNQKY 180
GPLLVDIIDP AKAYVQFLKE IFDFDLIKSF LAKQRKDKGW KLLFDSLNGI TGPYGKAIFV 240
DEFGLPAEEV LQNWHPLPDF GGLHPDPNLT YARTLVDRVD REKIAFGAAS DGDGDRNMIY 300
GYGPAFVSPG DSVAIIAEYA PEIPYFAKQG IYGLARSFPT SSAIDRVAAK KGLRCYEVPT 360
GWKFFCALFD AKKLSICGEE SFGTGSNHIR EKDGLWAIIA WLNILAIYHR RNPEKEASIK 420
TIQDEFWNEY GRTFFTRYDY EHIECEQAEK VVALLSEFVS RPNVCGSHFP ADESLTVIDC 480
GDFSYRDLDG SISENQGLFV KFSNGTKFVL RLSGTGSSGA TIRLYVEKYT DKKENYGQTA 540
DVFLKPVINS IVKFLRFKEI LGTDEPTVRT 570 |
Gene Ontology | GO:0005829; C:cytosol; IBA:RefGenome. GO:0000287; F:magnesium ion binding; IEA:InterPro. GO:0004614; F:phosphoglucomutase activity; IGI:SGD. GO:0019388; P:galactose catabolic process; IGI:SGD. GO:0019255; P:glucose 1-phosphate metabolic process; IGI:SGD. GO:0051156; P:glucose 6-phosphate metabolic process; ISS:SGD. GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW. GO:0005978; P:glycogen biosynthetic process; IGI:SGD. GO:0005992; P:trehalose biosynthetic process; IGI:SGD. GO:0006011; P:UDP-glucose metabolic process; IGI:SGD. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |