CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038606
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Kinesin-like protein KIF1C 
Protein Synonyms/Alias
  
Gene Name
 Kif1c 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
44IINPKQSKDAPKSFTacetylation[1, 2]
Reference
 [1] Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome.
 Hebert AS, Dittenhafer-Reed KE, Yu W, Bailey DJ, Selen ES, Boersma MD, Carson JJ, Tonelli M, Balloon AJ, Higbee AJ, Westphall MS, Pagliarini DJ, Prolla TA, Assadi-Porter F, Roy S, Denu JM, Coon JJ.
 Mol Cell. 2013 Jan 10;49(1):186-99. [PMID: 23201123]
 [2] Quantification of mitochondrial acetylation dynamics highlights prominent sites of metabolic regulation.
 Still AJ, Floyd BJ, Hebert AS, Bingman CA, Carson JJ, Gunderson DR, Dolan BK, Grimsrud PA, Dittenhafer-Reed KE, Stapleton DS, Keller MP, Westphall MS, Denu JM, Attie AD, Coon JJ, Pagliarini DJ.
 J Biol Chem. 2013 Jul 17;. [PMID: 23864654] 
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Complete proteome; Microtubule; Motor protein; Nucleotide-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1112 AA 
Protein Sequence
MAGASVKVAV RVRPFNARET SQDAKCVVSM QGNTTSIINP KQSKDAPKSF TFDYSYWSHT 60
SVEDPQFASQ QQVYRDIGEE MLLHAFEGYN VCIFAYGQTG AGKSYTMMGR QEPGQQGIVP 120
QLCEDLFSRV NVNQSAQLSY SVEVSYMEIY CERVRDLLNP KSRGSLRVRE HPILGPYVQD 180
LSKLAVTSYA DIADLMDCGN KARTVAATNM NETSSRSHAV FTIVFTQRSH DQLTGLDSEK 240
VSKISLVDLA GSERADSSGA RGMRLKEGAN INKSLTTLGK VISALADLQS KKRKSDFIPY 300
RDSVLTWLLK ENLGGNSRTA MIAALSPADI NYEETLSTLR YADRTKQIRC NAVINEDPNA 360
RLIRELQEEV ARLRDLLMAQ GLSASALGGL KVEEGSPGGV LPPASSPPAP ASPSSPPPHN 420
GELEPSFSPS AEPQIGPEEA MERLQETEKI IAELNETWEE KLRKTEALRM EREALLAEMG 480
VAVREDGGTV GVFSPKKTPH LVNLNEDPLM SECLLYHIKD GVTRVGQVDV DIKLTGQFIR 540
EQHCLFRSIP QPDGEVMVTL EPCEGAETYV NGKLVTEPLV LKSGNRIVMG KNHVFRFNHP 600
EQARLERERG VPPPPGPPSE PVDWNFAQKE LLEQQGIDIK LEMEKRLQDL ENQYRKEKEE 660
ADLLLEQQRL VRDTWGPTEP GQYADSDSGE DSDKRSCEES WRLISSLREQ LPPTTVQNIV 720
KRCGLPSSGK RRAPRRVYQI PQRRRLQGKD PRWATMADLK MQAVKEICYE VALADFRHGR 780
AEIEALAALK MRELCRTYGK PEGPGDAWRA VARDVWDTVG EEEGCGGGGG GSEEGARGAE 840
VEDLRAHIDK LTGILQEVKL QNSSKDRELQ ALRDRMLRME RVIPLTQDLE DDNDESGLVT 900
WAPPEGPEAV EETVPNDHSP AVRPTSPPLS SWERVSRLME EDPAFRRGRL RWLKQEQLRL 960
QGLQGAGGRG GGLRRPPARF VPPHDCKLRF PFKSNPQHRE SWPGMGSGEA PAPQPPEEVT 1020
VPPAPPNRRP PSPRRPHRSR RNSLDGGSRS RGGGSTQPEP QHLRPQKHNG YPQQPQPSPA 1080
QRPGPRYPPY TTPPRMRRQR SAPDLKESGA AV 1112 
Gene Ontology
 GO:0005794; C:Golgi apparatus; IDA:MGI.
 GO:0005874; C:microtubule; IEA:UniProtKB-KW.
 GO:0005875; C:microtubule associated complex; IEA:InterPro.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0003777; F:microtubule motor activity; IEA:InterPro.
 GO:0007018; P:microtubule-based movement; IEA:InterPro.
 GO:0006890; P:retrograde vesicle-mediated transport, Golgi to ER; IDA:MGI. 
Interpro
 IPR000253; FHA_dom.
 IPR019821; Kinesin_motor_CS.
 IPR001752; Kinesin_motor_dom.
 IPR027417; P-loop_NTPase.
 IPR008984; SMAD_FHA_domain. 
Pfam
 PF00498; FHA
 PF00225; Kinesin 
SMART
 SM00240; FHA
 SM00129; KISc 
PROSITE
 PS00411; KINESIN_MOTOR_DOMAIN1
 PS50067; KINESIN_MOTOR_DOMAIN2 
PRINTS
 PR00380; KINESINHEAVY.