CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-039249
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Calcium-transporting ATPase type 2C member 1 
Protein Synonyms/Alias
  
Gene Name
 Atp2c1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
190LVRCGKAKGIVIGTGubiquitination[1]
385RNNTLMGKPTEGALIacetylation[2]
475RDLYQQEKAQMGSAGubiquitination[1]
Reference
 [1] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113]
 [2] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Complete proteome; Hydrolase; Membrane; Nucleotide-binding; Reference proteome; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 884 AA 
Protein Sequence
ADLQNGLNKS EVSHRRAFHG WNEFDISEDE PLWKKYISQF KNPLIMLLLA SAVISVLMRQ 60
FDDAVSITVA ILIVVTVAFV QEYRSEKSLE ELSKLVPPEC HCVREGKLEH TLARDLVPGD 120
TVCLSVGDRV PADLRLFEAV DLSIDESSLT GETTPCSKVT APQPAATNGD LASRSNIAFM 180
GTLVRCGKAK GIVIGTGENS EFGEVFKMMQ AEEAPKTPLQ KSMDLLGKQL SFYSFGIIGI 240
IMLVGWLLGK DILEMFTISV SLAVAAIPEG LPIVVTVTLA LGVMRMVKKR AIVKKLPIVE 300
TLGCCNVICS DKTGTLTKNE MTVTHILTSD GLHAEVTGVG YNQFGEVIVD GDVVHGFYNP 360
AVSRIVEAGC VCNDAVIRNN TLMGKPTEGA LIALAMKMGL DGLQQDYIRK AEYPFSSEQK 420
WMAVKCVHRT QQDRPEICFM KGAYEQVIKY CTTYNSKGQT LALTQQQRDL YQQEKAQMGS 480
AGLRVLALAS GPDLGQLTFL GLVGIIDPPR TGVKEAVTTL IASGVSIKMI TGDSQETAIA 540
IASRLGLYSK TSQSVSGEEV DTMEVQHLSQ IVPKVAVFYR ASPRHKMKII KSLQKNGSVV 600
AMTGDGVNDA VALKAADIGV AMGQTGTDVC KEAADMILVD DDFQTIMSAI EEGKGIYNNI 660
KNFVRFQLST SIAALTLISL ATLMNFPNPL NAMQILWINI IMDGPPAQSL GVEPVDKDVI 720
RKPPRNWKDS ILTKNLILKI LVSSIIIVCG TLFVFWRELR DNVITPRDTT MTFTCFVFFD 780
MFNALSSRSQ CSSVFEIGLC SNKMFCYAVL GSIMGQLLVI YFPPLQKVFQ TESLSILDLL 840
FLLGLTSSVC IVSEIIKKVE RSREKTQKNA TSTPSSFLEP LPSI 884 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0005388; F:calcium-transporting ATPase activity; IEA:InterPro.
 GO:0046872; F:metal ion binding; IEA:InterPro. 
Interpro
 IPR006413; ATPase_P-typ_Ca-transp_PMR1.
 IPR006068; ATPase_P-typ_cation-transptr_C.
 IPR004014; ATPase_P-typ_cation-transptr_N.
 IPR023299; ATPase_P-typ_cyto_domN.
 IPR018303; ATPase_P-typ_P_site.
 IPR023298; ATPase_P-typ_TM_dom.
 IPR008250; ATPase_P-typ_transduc_dom_A.
 IPR001757; Cation_transp_P_typ_ATPase.
 IPR023214; HAD-like_dom. 
Pfam
 PF00689; Cation_ATPase_C
 PF00690; Cation_ATPase_N
 PF00122; E1-E2_ATPase
 PF00702; Hydrolase 
SMART
 SM00831; Cation_ATPase_N 
PROSITE
 PS00154; ATPASE_E1_E2 
PRINTS
 PR00119; CATATPASE.
 PR00120; HATPASE.