UniProt Accession

 GCSH_ECOLI; P0A6T9; P23884; Q2M9T7; Q8Z3W9 

Genbank Protein ID

 M57690; X73958; U28377; U00096; M97263; L20872; AP009048 

Genbank Nucleotide ID

 AAA68887.1; CAA52145.1; AAA69072.1; AAC75942.1; AAC36844.1; AAA23866.1; BAE76969.1 

Protein Name

 Glycine cleavage system H protein 

Protein Synonyms/Alias

  

Gene Name

 gcvH 

Gene Synonyms/Alias

 b2904; JW2872 

Created Date

 July 27, 2013 

Organism

 Escherichia coli (strain K12) 

NCBI Taxa ID

 83333 

Lysine Modification

Position	Peptide	Type	References
12	PAELKYSKEHEWLRK	acetylation	[1, 2]

Reference

 [1] Comprehensive profiling of protein lysine acetylation in Escherichia coli.
 Zhang K, Zheng S, Yang JS, Chen Y, Cheng Z.
 J Proteome Res. 2013 Feb 1;12(2):844-51. [PMID: 23294111]
 [2] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 

Functional Description

 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. 

Sequence Annotation

 MOD_RES 65 65 N6-lipoyllysine (By similarity).  

Keyword

 3D-structure; Complete proteome; Direct protein sequencing; Lipoyl; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 129 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IDA:EcoliWiki.
 GO:0005960; C:glycine cleavage complex; IEA:InterPro.
 GO:0031405; F:lipoic acid binding; ISS:EcoliWiki.
 GO:0019464; P:glycine decarboxylation via glycine cleavage system; ISS:EcoliWiki. 

Interpro

 IPR003016; 2-oxoA_DH_lipoyl-BS.
 IPR002930; GCV_H.
 IPR017453; GCV_H_sub.
 IPR011053; Single_hybrid_motif. 

Pfam

 PF01597; GCV_H 

SMART

  

PROSITE

 PS00189; LIPOYL 

PRINTS