CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-025971
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 3-hydroxybutyryl-CoA dehydrogenase 
Protein Synonyms/Alias
  
Gene Name
 GK3395 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Geobacillus kaustophilus (strain HTA426) 
NCBI Taxa ID
 235909 
Lysine Modification
Position
Peptide
Type
References
135AATKRPEKVIGMHFMacetylation[1]
Reference
 [1] Proteomic analysis of acetylation in thermophilic Geobacillus kaustophilus.
 Lee DW, Kim D, Lee YJ, Kim JA, Choi JY, Kang S, Pan JG.
 Proteomics. 2013 Aug;13(15):2278-82. [PMID: 23696451] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Oxidoreductase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 283 AA 
Protein Sequence
MDVKTIMVVG AGQMGSGIAQ VCAVAGYQVF LYDISEAQLD KGIANIEKGL ARQVEKGKMT 60
AVDKDAALAR LARSTDLHAA AEADLVIEAV VENMDVKTKL FAELDALARP ETILASNTSS 120
LPITEIAAAT KRPEKVIGMH FMNPVPVMKL VEIIRGLATA DDVYETIEAV ARKLGKVPVE 180
VNDFPGFISN RVLMPMINEA IYALYEGVAT KEAIDEVMKL GMNHPMGPLT LADFIGLDTC 240
LYIMETLHEG FGDDKYRPCP LLRKYVKAGW LGRKTGRGFY TYE 283 
Gene Ontology
 GO:0003857; F:3-hydroxyacyl-CoA dehydrogenase activity; IEA:InterPro.
 GO:0008691; F:3-hydroxybutyryl-CoA dehydrogenase activity; IEA:EC.
 GO:0070403; F:NAD+ binding; IEA:InterPro.
 GO:0006631; P:fatty acid metabolic process; IEA:InterPro. 
Interpro
 IPR022694; 3-OHacyl-CoA_DH.
 IPR006180; 3-OHacyl-CoA_DH_CS.
 IPR006176; 3-OHacyl-CoA_DH_NAD-bd.
 IPR006108; 3HC_DH_C.
 IPR008927; 6-PGluconate_DH_C-like.
 IPR013328; DH_multihelical.
 IPR016040; NAD(P)-bd_dom. 
Pfam
 PF00725; 3HCDH
 PF02737; 3HCDH_N 
SMART
  
PROSITE
 PS00067; 3HCDH 
PRINTS