CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-044076
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Thioredoxin 
Protein Synonyms/Alias
  
Gene Name
 TXN 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
39CGPCKMIKPFFHSLSubiquitination[1]
Reference
 [1] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789
Functional Description
  
Sequence Annotation
 DISULFID 32 35 Redox-active (By similarity).  
Keyword
  
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 105 AA 
Protein Sequence
MVKQIESKTA FQEALDAAGD KLVVVDFSAT WCGPCKMIKP FFHSLSEKYS NVIFLEVDVD 60
DCQDVASECE VKCMPTFQFF KKGQKVGEFS GANKEKLEAT INELV 105 
Gene Ontology
 GO:0030424; C:axon; IEA:Compara.
 GO:0005829; C:cytosol; IEA:Compara.
 GO:0030425; C:dendrite; IEA:Compara.
 GO:0005739; C:mitochondrion; IEA:Compara.
 GO:0043025; C:neuronal cell body; IEA:Compara.
 GO:0005634; C:nucleus; IEA:Compara.
 GO:0009055; F:electron carrier activity; IEA:InterPro.
 GO:0015037; F:peptide disulfide oxidoreductase activity; IEA:Compara.
 GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
 GO:0016999; P:antibiotic metabolic process; IEA:Compara.
 GO:0045454; P:cell redox homeostasis; IEA:Compara.
 GO:0035690; P:cellular response to drug; IEA:Compara.
 GO:0071333; P:cellular response to glucose stimulus; IEA:Compara.
 GO:0071455; P:cellular response to hyperoxia; IEA:Compara.
 GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
 GO:0046826; P:negative regulation of protein export from nucleus; IEA:Compara.
 GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Compara.
 GO:0014823; P:response to activity; IEA:Compara.
 GO:0048678; P:response to axon injury; IEA:Compara.
 GO:0071548; P:response to dexamethasone stimulus; IEA:Compara.
 GO:0010269; P:response to selenium ion; IEA:Compara.
 GO:0097068; P:response to thyroxine stimulus; IEA:Compara. 
Interpro
 IPR005746; Thioredoxin.
 IPR012336; Thioredoxin-like_fold.
 IPR017937; Thioredoxin_CS.
 IPR013766; Thioredoxin_domain. 
Pfam
 PF00085; Thioredoxin 
SMART
  
PROSITE
 PS00194; THIOREDOXIN_1
 PS51352; THIOREDOXIN_2 
PRINTS
 PR00421; THIOREDOXIN.