UniProt Accession

 ATP4B_RAT; P18598 

Genbank Protein ID

 L34666; L34661; L34662; L34663; L34664; L34665; S76404; M55655; M35535 

Genbank Nucleotide ID

 AAA41332.1; AAA41332.1; AAA41332.1; AAA41332.1; AAA41332.1; AAA41332.1; AAB21120.1; AAA41330.1; AAA63482.1 

Protein Name

 Potassium-transporting ATPase subunit beta 

Protein Synonyms/Alias

 Gastric H(+)/K(+) ATPase subunit beta; Proton pump beta chain 

Gene Name

 Atp4b 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Rattus norvegicus (Rat) 

NCBI Taxa ID

 10116 

Lysine Modification

Position	Peptide	Type	References
252	SNPLVAAKFLNVPKN	acetylation	[1]
285	PHDPYEGKVEFKLTI	acetylation	[1]

Reference

 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 

Functional Description

 Required for stabilization and maturation of the catalytic proton pump alpha subunit and may also involved in cell adhesion and establishing epithelial cell polarity (By similarity). 

Sequence Annotation

 REGION 194 294 immunoglobulin-like (By similarity).
 CARBOHYD 99 99 N-linked (GlcNAc...) (Potential).
 CARBOHYD 103 103 N-linked (GlcNAc...) (Potential).
 CARBOHYD 130 130 N-linked (GlcNAc...) (Potential).
 CARBOHYD 146 146 N-linked (GlcNAc...) (Potential).
 CARBOHYD 161 161 N-linked (GlcNAc...) (Potential).
 CARBOHYD 193 193 N-linked (GlcNAc...) (Potential).
 CARBOHYD 225 225 N-linked (GlcNAc...) (Potential).
 DISULFID 131 152 By similarity.
 DISULFID 162 178 By similarity.
 DISULFID 201 266 By similarity.  

Keyword

 Cell adhesion; Cell membrane; Complete proteome; Disulfide bond; Glycoprotein; Hydrogen ion transport; Ion transport; Membrane; Potassium; Potassium transport; Reference proteome; Signal-anchor; Transmembrane; Transmembrane helix; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 294 AA 

Protein Sequence

Gene Ontology

 GO:0005890; C:sodium:potassium-exchanging ATPase complex; IEA:InterPro.
 GO:0008900; F:hydrogen:potassium-exchanging ATPase activity; TAS:RGD.
 GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
 GO:0001696; P:gastric acid secretion; TAS:RGD.
 GO:0032496; P:response to lipopolysaccharide; IEP:RGD.
 GO:0010243; P:response to organic nitrogen; IEP:RGD.
 GO:0006814; P:sodium ion transport; IEA:InterPro. 

Interpro

 IPR000402; Na/K_ATPase_sub_beta. 

Pfam

 PF00287; Na_K-ATPase 

SMART

  

PROSITE

 PS00390; ATPASE_NA_K_BETA_1
 PS00391; ATPASE_NA_K_BETA_2 

PRINTS