CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-000346
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Zinc finger protein 609 
Protein Synonyms/Alias
  
Gene Name
 ZNF609 
Gene Synonyms/Alias
 KIAA0295 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
794SIKAEADKIYSFTDNacetylation[1]
927ESQALKTKRDEEPESubiquitination[2]
1148WTYVYPAKYSDIKSEubiquitination[3]
Reference
 [1] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [3] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965] 
Functional Description
  
Sequence Annotation
 ZN_FING 495 520 C2H2-type.
 MOD_RES 358 358 Phosphoserine.
 MOD_RES 576 576 Phosphoserine.
 MOD_RES 578 578 Phosphoserine.
 MOD_RES 746 746 Phosphothreonine.
 MOD_RES 804 804 Phosphoserine.
 MOD_RES 842 842 Phosphoserine.
 MOD_RES 846 846 Phosphoserine.
 MOD_RES 849 849 Phosphoserine.
 MOD_RES 1055 1055 Phosphoserine.  
Keyword
 Complete proteome; Metal-binding; Nucleus; Phosphoprotein; Reference proteome; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1411 AA 
Protein Sequence
MSLSSGASGG KGVDANPVET YDSGDEWDIG VGNLIIDLDA DLEKDQQKLE MSGSKEVGIP 60
APNAVATLPD NIKFVTPVPG PQGKEGKSKS KRSKSGKDTS KPTPGTSLFT PSEGAASKKE 120
VQGRSGDGAN AGGLVAAIAP KGSEKAAKAS RSVAGSKKEK ENSSSKSKKE RSEGVGTCSE 180
KDPGVLQPVP LGGRGGQYDG SAGVDTGAVE PLGSIAIEPG AALNPLGTKP EPEEGENECR 240
LLKKVKSEKM ESPVSTPAVL PIHLLVPVVN NDISSPCEQI MVRTRSVGVN TCDVALATEP 300
ECLGPCEPGT SVNLEGIVWQ ETEDGMLVVN VTWRNKTYVG TLLDCTRHDW APPRFCDSPT 360
SDLEMRNGRG RGKRMRPNSN TPVNETATAS DSKGTSNSSK TRAGANSKGR RGSQNSSEHR 420
PPASSTSEDV KASPSSANKR KNKPLSDMEL NSSSEDSKGS KRVRTNSMGS ATGPLPGTKV 480
EPTVLDRNCP SPVLIDCPHP NCNKKYKHIN GLKYHQAHAH TDDDSKPEAD GDSEYGEEPI 540
LHADLGSCNG ASVSQKGSLS PARSATPKVR LVEPHSPSPS SKFSTKGLCK KKLSGEGDTD 600
LGALSNDGSD DGPSVMDETS NDAFDSLERK CMEKEKCKKP SSLKPEKIPS KSLKSARPIA 660
PAIPPQQIYT FQTATFTAAS PGSSSGLTAT VAQAMPNSPQ LKPIQPKPTV MGEPFTVNPA 720
LTPAKDKKKK DKKKKESSKE LESPLTPGKV CRAEEGKSPF RESSGDGMKM EGLLNGSSDP 780
HQSRLASIKA EADKIYSFTD NAPSPSIGGS SRLENTTPTQ PLTPLHVVTQ NGAEASSVKT 840
NSPAYSDISD AGEDGEGKVD SVKSKDAEQL VKEGAKKTLF PPQPQSKDSP YYQGFESYYS 900
PSYAQSSPGA LNPSSQAGVE SQALKTKRDE EPESIEGKVK NDICEEKKPE LSSSSQQPSV 960
IQQRPNMYMQ SLYYNQYAYV PPYGYSDQSY HTHLLSTNTA YRQQYEEQQK RQSLEQQQRG 1020
VDKKAEMGLK EREAALKEEW KQKPSIPPTL TKAPSLTDLV KSGPGKAKEP GADPAKSVII 1080
PKLDDSSKLP GQAPEGLKVK LSDASHLSKE ASEAKTGAEC GRQAEMDPIL WYRQEAEPRM 1140
WTYVYPAKYS DIKSEDERWK EERDRKLKEE RSRSKDSVPK EDGKESTSSD CKLPTSEESR 1200
LGSKEPRPSV HVPVSSPLTQ HQSYIPYMHG YSYSQSYDPN HPSYRSMPAV MMQNYPGSYL 1260
PSSYSFSPYG SKVSGGEDAD KARASPSVTC KSSSESKALD ILQQHASHYK SKSPTISDKT 1320
SQERDRGGCG VVGGGGSCSS VGGASGGERS VDRPRTSPSQ RLMSTHHHHH HLGYSLLPAQ 1380
YNLPYAAGLS STAIVASQQG STPSLYPPPR R 1411 
Gene Ontology
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0008270; F:zinc ion binding; IEA:InterPro. 
Interpro
 IPR007087; Znf_C2H2.
 IPR015880; Znf_C2H2-like. 
Pfam
  
SMART
 SM00355; ZnF_C2H2 
PROSITE
 PS00028; ZINC_FINGER_C2H2_1
 PS50157; ZINC_FINGER_C2H2_2 
PRINTS