CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-021388
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 PR domain zinc finger protein 13 
Protein Synonyms/Alias
 PR domain-containing protein 13 
Gene Name
 PRDM13 
Gene Synonyms/Alias
 PFM10 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
580HLCLYCGKLYSRKYGacetylation[1]
Reference
 [1] Regulation of cellular metabolism by protein lysine acetylation.
 Zhao S, Xu W, Jiang W, Yu W, Lin Y, Zhang T, Yao J, Zhou L, Zeng Y, Li H, Li Y, Shi J, An W, Hancock SM, He F, Qin L, Chin J, Yang P, Chen X, Lei Q, Xiong Y, Guan KL.
 Science. 2010 Feb 19;327(5968):1000-4. [PMID: 20167786] 
Functional Description
 May be involved in transcriptional regulation. 
Sequence Annotation
 DOMAIN 1 112 SET.
 ZN_FING 137 159 C2H2-type 1.
 ZN_FING 573 595 C2H2-type 2.
 ZN_FING 601 623 C2H2-type 3.
 ZN_FING 630 653 C2H2-type 4.  
Keyword
 Complete proteome; DNA-binding; Metal-binding; Methyltransferase; Nucleus; Reference proteome; Repeat; S-adenosyl-L-methionine; Transcription; Transcription regulation; Transferase; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 707 AA 
Protein Sequence
MHGAARAPAT SVSADCCIPA GLRLGPVPGT FKLGKYLSDR REPGPKKKVR MVRGELVDES 60
GGSPLEWIGL IRAARNSQEQ TLEAIADLPG GQIFYRALRD VQPGEELTVW YSNSLAQWFD 120
IPTTATPTHD EKGEERYICW YCWRTFRYPN SLKAHLRFHC VFSGGGGGAF LHHEHAARQG 180
AVPAADGLGL SPKPPAPDFA APSQAGTLRP HPLGPPPVQA CGAREGIKRE ASSAPSATSP 240
TPGKWGQPKK GKEQLDRALD MSGAARGQGH FLGIVGGSSA GVGSLAFYPG VRSAFKPAGL 300
ARAAAAAHGD PYREESSSKQ GAGLALGRLL GGGRACGRPG SGENSAAGGA GHHHHHHAHH 360
HHHPKCLLAG DPPPPPPPGL PCSGALRGFP LLSVPPEEAS AFKHVERAPP AAAALPGARY 420
AQLPPAPGLP LERCALPPLD PGGLKAYPGG ECSHLPAVMP AFTVYNGELL YGSPATTAYY 480
PLKLHFGGLL KYPESISYFS GPAAAALSPA ELGSLASIDR EIAMHNQQLS EMAAGKGRGR 540
LDSGTLPPAV AAAGGTGGGG SGGSGAGKPK TGHLCLYCGK LYSRKYGLKI HMRTHTGYKP 600
LKCKVCLRPF GDPSNLNKHI RLHAEGNTPY RCEFCGKVLV RRRDLERHVK SRHPGQSLLA 660
KAGDGPGAEP GYPPEPGDPK SDDSDVDVCF TDDQSDPEVG GGGERDL 707 
Gene Ontology
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0022008; P:neurogenesis; IEA:Compara.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 
Interpro
 IPR001214; SET_dom.
 IPR007087; Znf_C2H2.
 IPR015880; Znf_C2H2-like.
 IPR013087; Znf_C2H2/integrase_DNA-bd. 
Pfam
 PF00096; zf-C2H2 
SMART
 SM00317; SET
 SM00355; ZnF_C2H2 
PROSITE
 PS50280; SET
 PS00028; ZINC_FINGER_C2H2_1
 PS50157; ZINC_FINGER_C2H2_2 
PRINTS