| Tag | Content |
|---|
| CPLM ID | CPLM-014321 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Beta-2-syntrophin |
Protein Synonyms/Alias | 59 kDa dystrophin-associated protein A1 basic component 2; Syntrophin-3; SNT3; Syntrophin-like; SNTL |
Gene Name | Sntb2 |
Gene Synonyms/Alias | Snt2b2 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 111 | GGLGISIKGGRENRM | ubiquitination | [1] | | 168 | QALKRAGKEVLLEVK | ubiquitination | [1] | | 317 | AWLAEQAKLDGGRQQ | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Adapter protein that binds to and probably organizes the subcellular localization of a variety of membrane proteins. May link various receptors to the actin cytoskeleton and the dystrophin glycoprotein complex. May play a role in the regulation of secretory granules via its interaction with PTPRN (By similarity). |
Sequence Annotation | DOMAIN 95 178 PDZ.
DOMAIN 143 280 PH 1.
DOMAIN 305 417 PH 2.
DOMAIN 464 520 SU.
REGION 498 520 Calmodulin-binding (By similarity).
MOD_RES 75 75 Phosphoserine.
MOD_RES 90 90 Phosphoserine.
MOD_RES 202 202 Phosphoserine (By similarity).
MOD_RES 213 213 Phosphoserine (By similarity).
MOD_RES 373 373 Phosphoserine (By similarity). |
Keyword | Actin-binding; Calcium; Calmodulin-binding; Cell junction; Complete proteome; Cytoplasm; Cytoplasmic vesicle; Cytoskeleton; Membrane; Microtubule; Phosphoprotein; Reference proteome; Repeat. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 520 AA |
Protein Sequence | MAVWTRATKA GLVELLLRER WVRVVAELSG ESLSLTGDAA AVEPEPPAAA FNGLPNGGGG 60
ESLPGSPNRG LGPPSPPAPP RGPAGEASAS PPVRRVRVVK QEAGGLGISI KGGRENRMPI 120
LISKIFPGLA ADQSRALRLG DAILSVNGTD LRQATHDQAV QALKRAGKEV LLEVKFIREV 180
TPYIKKPSLV SDLPWEGASP QSPSFSGSED SGSPKHQNTT KDRKVIPLKM CFAARNLSMP 240
DLENRLIELH SPDSRNTLIL RCKDTATAHS WFVAIHTNIM ALLPQVLAEL NAMLGATSTA 300
GGSKEVKHIA WLAEQAKLDG GRQQWRPVLM AVTEKDLLLY DCMPWTRDAW ASPCHSYPLV 360
ATRLVHSGSG CRSPSLGSDL TFATRTGSRQ GIEMHLFRVE THRDLSTWTR ILVQGCHAAA 420
ELIKEVSLGC TLSGQEVRFT VHYEHGFTIT RDNGGASSIL YRYPFERLKM SADDGIRNLY 480
LDFGGPEGEL TMDLHSCPKP IVFVLHTFLS AKVTRMGLLV 520 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |