CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-033288
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 AF4/FMR2 family member 4 
Protein Synonyms/Alias
  
Gene Name
 AFF4 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
63LGNYDEMKDFIGDRSubiquitination[1]
107GGSHQSSKWTPVGPAubiquitination[2]
Reference
 [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661]
 [2] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 148 AA 
Protein Sequence
MNREDRNVLR MKERERRNQE IQQGEDAFPP SSPLFAEPYK VTSKEDKLSS RIQSMLGNYD 60
EMKDFIGDRS IPKLVAIPKP TVPPSADEKS NPNFFEQRHG GSHQSSKWTP VGPAPSTSQS 120
QKRSSGLQSG HSSQRTSAGS SSGTNSSG 148 
Gene Ontology
 GO:0005634; C:nucleus; IEA:Compara.
 GO:0007286; P:spermatid development; IEA:Compara. 
Interpro
 IPR007797; TF_AF4/FMR2. 
Pfam
 PF05110; AF-4 
SMART
  
PROSITE
  
PRINTS