UniProt Accession

 ALBA1_SULSO; P60849; P74761; Q97ZF6 

Genbank Protein ID

 AJ298830; AE006641 

Genbank Nucleotide ID

 CAC12668.1; AAK41236.1 

Protein Name

 DNA/RNA-binding protein Alba 1 

Protein Synonyms/Alias

 Sso10b 

Gene Name

 albA1 

Gene Synonyms/Alias

 sso10b; SSO0962 

Created Date

 July 27, 2013 

Organism

 Sulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322  

NCBI Taxa ID

 273057 

Lysine Modification

Position	Peptide	Type	References
16	SNVVLIGKKPVMNYV	acetylation	[1, 2]

Reference

 [1] The interaction of Alba, a conserved archaeal chromatin protein, with Sir2 and its regulation by acetylation.
 Bell SD, Botting CH, Wardleworth BN, Jackson SP, White MF.
 Science. 2002 Apr 5;296(5565):148-51. [PMID: 11935028]
 [2] Sir2 and the acetyltransferase, Pat, regulate the archaeal chromatin protein, Alba.
 Marsh VL, Peak-Chew SY, Bell SD.
 J Biol Chem. 2005 Jun 3;280(22):21122-8. [PMID: 15824122] 

Functional Description

 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. May be involved in DNA compaction. May bind rRNA and mRNA, playing a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes. 

Sequence Annotation

 MOD_RES 2 2 N-acetylserine.
 MOD_RES 17 17 N6-acetyllysine.  

Keyword

 3D-structure; Acetylation; Chromosome; Complete proteome; Cytoplasm; DNA condensation; DNA-binding; Reference proteome; RNA-binding. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 97 AA 

Protein Sequence

Gene Ontology

 GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0003690; F:double-stranded DNA binding; IEA:HAMAP.
 GO:0003723; F:RNA binding; IEA:HAMAP.
 GO:0030261; P:chromosome condensation; IEA:UniProtKB-KW. 

Interpro

 IPR013795; DNA/RNA-bd_Alba.
 IPR002775; DNA/RNA-bd_Alba-like. 

Pfam

 PF01918; Alba 

SMART

  

PROSITE

  

PRINTS