UniProt Accession

 PCLI1_MOUSE; Q3UBG2; Q3UAR0; Q68EE9; Q7TPS1 

Genbank Protein ID

 AK150971; AK151267; AK162081; BC054112; BC080290 

Genbank Nucleotide ID

 BAE30002.1; BAE30254.1; BAE36714.1; AAH54112.1; AAH80290.1 

Protein Name

 PTB-containing, cubilin and LRP1-interacting protein 

Protein Synonyms/Alias

 P-CLI1; Phosphotyrosine interaction domain-containing protein 1 

Gene Name

 Pid1 

Gene Synonyms/Alias

 Pcli1 

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
17	QHFQTMLKSKLNVLT	ubiquitination	[1]
19	FQTMLKSKLNVLTLK	ubiquitination	[1]
80	FLSGCTEKPVIELWK	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

 Increases proliferation of preadipocytes without affecting adipocytic differentiation (By similarity). 

Sequence Annotation

 DOMAIN 60 217 PID.
 MOD_RES 202 202 Phosphoserine.
 MOD_RES 203 203 Phosphoserine.
 MOD_RES 214 214 Phosphoserine.  

Keyword

 Alternative splicing; Complete proteome; Cytoplasm; Phosphoprotein; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 217 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IDA:BHF-UCL.
 GO:0005739; C:mitochondrion; IEA:Compara.
 GO:0005634; C:nucleus; IEA:Compara.
 GO:0071398; P:cellular response to fatty acid; IDA:BHF-UCL.
 GO:0071354; P:cellular response to interleukin-6; IDA:BHF-UCL.
 GO:0044320; P:cellular response to leptin stimulus; IDA:BHF-UCL.
 GO:0071356; P:cellular response to tumor necrosis factor; IDA:BHF-UCL.
 GO:0070584; P:mitochondrion morphogenesis; IEA:Compara.
 GO:2001170; P:negative regulation of ATP biosynthetic process; IEA:Compara.
 GO:0090005; P:negative regulation of establishment of protein localization to plasma membrane; IEA:Compara.
 GO:0046325; P:negative regulation of glucose import; IMP:BHF-UCL.
 GO:2001274; P:negative regulation of glucose import in response to insulin stimulus; IEA:Compara.
 GO:0046627; P:negative regulation of insulin receptor signaling pathway; IEA:Compara.
 GO:0090298; P:negative regulation of mitochondrial DNA replication; IEA:Compara.
 GO:0001933; P:negative regulation of protein phosphorylation; IEA:Compara.
 GO:2001171; P:positive regulation of ATP biosynthetic process; IMP:BHF-UCL.
 GO:0070346; P:positive regulation of fat cell proliferation; IEA:Compara.
 GO:2000379; P:positive regulation of reactive oxygen species metabolic process; IEA:Compara.
 GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Compara.
 GO:2000045; P:regulation of G1/S transition of mitotic cell cycle; IEA:Compara.
 GO:0051881; P:regulation of mitochondrial membrane potential; IMP:BHF-UCL.
 GO:2000377; P:regulation of reactive oxygen species metabolic process; IMP:BHF-UCL. 

Interpro

 IPR011993; PH_like_dom.
 IPR006020; PTyr_interaction_dom. 

Pfam

 PF00640; PID 

SMART

  

PROSITE

 PS01179; PID 

PRINTS