CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-021714
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Solute carrier family 13 member 1 
Protein Synonyms/Alias
 NaSi-1; Renal sodium/sulfate cotransporter; Na(+)/sulfate cotransporter 
Gene Name
 Slc13a1 
Gene Synonyms/Alias
 Nas1; Nasi1 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
220SRKMETEKNAVTGAKubiquitination[1]
330LKEKACAKVIKQEYEubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
 Sodium/sulfate cotransporter that mediates sulfate reabsorption in the kidney. 
Sequence Annotation
 CARBOHYD 174 174 N-linked (GlcNAc...) (Potential).
 CARBOHYD 590 590 N-linked (GlcNAc...) (Potential).  
Keyword
 Alternative splicing; Complete proteome; Glycoprotein; Ion transport; Membrane; Reference proteome; Sodium; Sodium transport; Sulfate transport; Symport; Transmembrane; Transmembrane helix; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 594 AA 
Protein Sequence
MKLLNYALVY RRFLLVVFTI LVFLPLPLII RTKEAQCAYI LFVIAIFWIT EALPLSITAL 60
LPGLMFPMFG IMRSSQVASA YFKDFHLLLI GVICLATSIE KWNLHKRIAL RMVMMVGVNP 120
AWLTLGFMSS TAFLSMWLSN TSTAAMVMPI VEAVAQQIIS AEAEAEATQM TYFNESAAHG 180
LDIDETVIGQ ETNEKKEKTK PAPGSSHDKG KVSRKMETEK NAVTGAKYRS RKDHMMCKLM 240
CLSVAYSSTI GGLTTITGTS TNLIFSEHFN TRYPDCRCLN FGSWFLFSFP VALILLLLSW 300
IWLQWLYLGF DFKMFKCGKT KTLKEKACAK VIKQEYEKLG PMRYQEIVTL VIFIVMALLW 360
FSRDPGFVTG WSVLFSEYPG YVTDSTVALV AGILFFLIPA KKVTKMTSAG EIIAFDYTPL 420
ITWKEFQSFM PWDIAILVGG GFALADGCQV SGLSNWIGSK LSPLGSLPVW LIILISSLIV 480
TSLTEVASNP ATITILFPIL SPLAEAIQVN PLQILLPSTL CTSFAFLLPV ANPPNAIVFS 540
YGHLKVIDMV KAGLGVNILG VAVVMLGMFT WIEPMFNLHE YPSWASNFVN QTMP 594 
Gene Ontology
 GO:0005887; C:integral to plasma membrane; ISS:MGI.
 GO:0008271; F:secondary active sulfate transmembrane transporter activity; IDA:MGI.
 GO:0015382; F:sodium:sulfate symporter activity; IEA:Compara.
 GO:0008272; P:sulfate transport; IDA:MGI. 
Interpro
 IPR001898; Na/sul_symport. 
Pfam
 PF00939; Na_sulph_symp 
SMART
  
PROSITE
 PS01271; NA_SULFATE 
PRINTS