Tag | Content |
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CPLM ID | CPLM-021714 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Solute carrier family 13 member 1 |
Protein Synonyms/Alias | NaSi-1; Renal sodium/sulfate cotransporter; Na(+)/sulfate cotransporter |
Gene Name | Slc13a1 |
Gene Synonyms/Alias | Nas1; Nasi1 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
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220 | SRKMETEKNAVTGAK | ubiquitination | [1] | 330 | LKEKACAKVIKQEYE | ubiquitination | [1] |
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Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Sodium/sulfate cotransporter that mediates sulfate reabsorption in the kidney. |
Sequence Annotation | CARBOHYD 174 174 N-linked (GlcNAc...) (Potential). CARBOHYD 590 590 N-linked (GlcNAc...) (Potential). |
Keyword | Alternative splicing; Complete proteome; Glycoprotein; Ion transport; Membrane; Reference proteome; Sodium; Sodium transport; Sulfate transport; Symport; Transmembrane; Transmembrane helix; Transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 594 AA |
Protein Sequence | MKLLNYALVY RRFLLVVFTI LVFLPLPLII RTKEAQCAYI LFVIAIFWIT EALPLSITAL 60 LPGLMFPMFG IMRSSQVASA YFKDFHLLLI GVICLATSIE KWNLHKRIAL RMVMMVGVNP 120 AWLTLGFMSS TAFLSMWLSN TSTAAMVMPI VEAVAQQIIS AEAEAEATQM TYFNESAAHG 180 LDIDETVIGQ ETNEKKEKTK PAPGSSHDKG KVSRKMETEK NAVTGAKYRS RKDHMMCKLM 240 CLSVAYSSTI GGLTTITGTS TNLIFSEHFN TRYPDCRCLN FGSWFLFSFP VALILLLLSW 300 IWLQWLYLGF DFKMFKCGKT KTLKEKACAK VIKQEYEKLG PMRYQEIVTL VIFIVMALLW 360 FSRDPGFVTG WSVLFSEYPG YVTDSTVALV AGILFFLIPA KKVTKMTSAG EIIAFDYTPL 420 ITWKEFQSFM PWDIAILVGG GFALADGCQV SGLSNWIGSK LSPLGSLPVW LIILISSLIV 480 TSLTEVASNP ATITILFPIL SPLAEAIQVN PLQILLPSTL CTSFAFLLPV ANPPNAIVFS 540 YGHLKVIDMV KAGLGVNILG VAVVMLGMFT WIEPMFNLHE YPSWASNFVN QTMP 594 |
Gene Ontology | GO:0005887; C:integral to plasma membrane; ISS:MGI. GO:0008271; F:secondary active sulfate transmembrane transporter activity; IDA:MGI. GO:0015382; F:sodium:sulfate symporter activity; IEA:Compara. GO:0008272; P:sulfate transport; IDA:MGI. |
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