CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-031519
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 cDNA FLJ61052, highly similar to Homo sapiens myosin head domain containing 1 (MYOHD1), transcript variant 2, mRNA 
Protein Synonyms/Alias
  
Gene Name
  
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
838ELDGVEEKHFSQAPCubiquitination[1]
Reference
 [1] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965] 
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Motor protein; Myosin; Nucleotide-binding. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 970 AA 
Protein Sequence
MLQQVNGHNP GSDGQAREYL REDLQEFLGG EVLLYKLDDL TRVNPVTLET VLRCLQARYM 60
ADTFYTNAGC TLVALNPFKP VPQLYSPELM REYHAAPQPQ KLKPHVFTVG EQTYRNVKSL 120
IEPVNQSIVV SGESGAGKTW TSRCLMKFYA VVATSPASWE SHKIAERIEQ RILNSNPVME 180
AFGNACTLRN NNSSRFGKFI QLQLNRAQQM TGAAVQTYLL EKTRVACQAS SERNFHIFYQ 240
ICKGASEDER LQWHLPEGAA FSWLPNPERS SEEDCFEVTR EAMLHLGIDT PTQNNIFKVL 300
AGLLHLGNIQ FAASEDEAQP CQPMDDAKYS VRTAASLLGL PEDVLLEMVQ IRTIRAGRQQ 360
QVFRKPCARA ECDTRRDCLA KLIYARLFDW LVSVINSSIC ADTDSWTTFI GLLDVYGFES 420
FPDNSLEQLC INYANEKLQQ HFVAHYLRAQ QEEYAVEGLE WSFINYQDNQ PCLDLIEGSP 480
ISICSLINEE CRLNRPSSAA QLQTRIETAL AGSPCLGHNK LSREPSFIVV HYAGPVRYHT 540
AGLVEKNKDP IPPELTRLLQ QSQDPLLMGL FPTNPKEKTQ EEPPGQSRAP VLTVVSKFKA 600
SLEQLLQVLH STTPHYIRCI KPNSQGQAQT FLQEEVLSQL EACGLVETIH ISAAGFPIRV 660
SHRNFVERYK LLRRLHPCTS SGPDSPYPAK GLPEWCPHSE EATLEPLIQD ILHTLPVLTQ 720
AAAITGDSAE AMPAPMHCGR TKVFMTDSML ELLECGRARV LEQCARCIQG GWRRHRHREQ 780
ERQWRAVMLI QAAIRSWLTR KHIQRLHAAA TVIKRAWQKW RIRMACLAAK ELDGVEEKHF 840
SQAPCSLSTS PLQTRLLEAI IRFWPLGLVL ANTAMGVGSF QRKLVVWACL QLPRGSPSSY 900
TVQTAQDQAG VTSIRALPQG SIKFHCRKSP LRYADICPEP SPYSITGFNQ ILLERHRLIH 960
VTSSAFTGLG 970 
Gene Ontology
 GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0003774; F:motor activity; IEA:InterPro. 
Interpro
 IPR000048; IQ_motif_EF-hand-BS.
 IPR001609; Myosin_head_motor_dom.
 IPR027417; P-loop_NTPase. 
Pfam
 PF00063; Myosin_head 
SMART
 SM00015; IQ
 SM00242; MYSc 
PROSITE
 PS50096; IQ 
PRINTS
 PR00193; MYOSINHEAVY.