UniProt Accession

 G3XAJ1_HUMAN; G3XAJ1 

Genbank Protein ID

 AL137881; CH471075 

Genbank Nucleotide ID

 EAX08864.1 

Protein Name

 Deleted in leukemia 8 protein, isoform CRA_b 

Protein Synonyms/Alias

 Ribonuclease H2 subunit B 

Gene Name

 RNASEH2B 

Gene Synonyms/Alias

 FLJ11712; hCG_28706 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
136	LKLPGLEKLLHHVTE	ubiquitination	[1]
145	LHHVTEEKGNPEIDN	ubiquitination	[1, 2]
153	GNPEIDNKKYYKYSK	ubiquitination	[2]
154	NPEIDNKKYYKYSKE	ubiquitination	[2]
170	TLKWLEKKVNQTVAA	ubiquitination	[2]
179	NQTVAALKTNNVNVS	ubiquitination	[2]
204	GDQASTDKEEDYIRY	ubiquitination	[2]
222	LISDYIPKELSDDLS	ubiquitination	[2]
230	ELSDDLSKYLKLPEP	ubiquitination	[1, 2, 3]

Reference

 [1] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [3] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 257 AA 

Protein Sequence

Gene Ontology

 GO:0005634; C:nucleus; IDA:HPA. 

Interpro

 IPR019024; RNase_H2_suB. 

Pfam

 PF09468; RNase_H2-Ydr279 

SMART

  

PROSITE

  

PRINTS