| Tag | Content |
|---|
| CPLM ID | CPLM-023675 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Zinc finger protein with KRAB and SCAN domains 5 |
Protein Synonyms/Alias | Zinc finger protein 95 homolog; Zfp-95 |
Gene Name | ZKSCAN5 |
Gene Synonyms/Alias | KIAA1015; ZFP95 |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 303 | FAEVSDLKGMVQRWQ | ubiquitination | [1] | | 509 | EGCEFQGKLDRKQGI | ubiquitination | [1] |
|
Reference | [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments. Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA. Mol Cell Proteomics. 2013 Mar;12(3):825-31. [ PMID: 23266961] |
Functional Description | May be involved in transcriptional regulation. |
Sequence Annotation | DOMAIN 51 132 SCAN box.
DOMAIN 218 291 KRAB.
ZN_FING 346 368 C2H2-type 1.
ZN_FING 374 396 C2H2-type 2.
ZN_FING 402 424 C2H2-type 3.
ZN_FING 430 452 C2H2-type 4.
ZN_FING 549 571 C2H2-type 5.
ZN_FING 577 599 C2H2-type 6.
ZN_FING 605 627 C2H2-type 7.
ZN_FING 633 655 C2H2-type 8.
ZN_FING 661 683 C2H2-type 9.
ZN_FING 717 739 C2H2-type 10.
ZN_FING 745 763 C2H2-type 11; atypical.
ZN_FING 773 795 C2H2-type 12.
ZN_FING 801 823 C2H2-type 13. |
Keyword | 3D-structure; Complete proteome; DNA-binding; Metal-binding; Nucleus; Reference proteome; Repeat; Transcription; Transcription regulation; Zinc; Zinc-finger. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 839 AA |
Protein Sequence | MIMTESREVI DLDPPAETSQ EQEDLFIVKV EEEDCTWMQE YNPPTFETFY QRFRHFQYHE 60
ASGPREALSQ LRVLCCEWLR PELHTKEQIL ELLVLEQFLT ILPEEFQPWV REHHPESGEE 120
AVAVIENIQR ELEERRQQIV ACPDVLPRKM ATPGAVQESC SPHPLTVDTQ PEQAPQKPRL 180
LEENALPVLQ VPSLPLKDSQ ELTASLLSTG SQKLVKIEEV ADVAVSFILE EWGHLDQSQK 240
SLYRDDRKEN YGSITSMGYE SRDNMELIVK QISDDSESHW VAPEHTERSV PQDPDFAEVS 300
DLKGMVQRWQ VNPTVGKSRQ NPSQKRDLDA ITDISPKQST HGERGHRCSD CGKFFLQASN 360
FIQHRRIHTG EKPFKCGECG KSYNQRVHLT QHQRVHTGEK PYKCQVCGKA FRVSSHLVQH 420
HSVHSGERPY GCNECGKNFG RHSHLIEHLK RHFREKSQRC SDKRSKNTKL SVKKKISEYS 480
EADMELSGKT QRNVSQVQDF GEGCEFQGKL DRKQGIPMKE ILGQPSSKRM NYSEVPYVHK 540
KSSTGERPHK CNECGKSFIQ SAHLIQHQRI HTGEKPFRCE ECGKSYNQRV HLTQHQRVHT 600
GEKPYTCPLC GKAFRVRSHL VQHQSVHSGE RPFKCNECGK GFGRRSHLAG HLRLHSREKS 660
HQCRECGEIF FQYVSLIEHQ VLHMGQKNEK NGICEEAYSW NLTVIEDKKI ELQEQPYQCD 720
ICGKAFGYSS DLIQHYRTHT AEKPYQCDIC RENVGQCSHT KQHQKIYSST KSHQCHECGR 780
GFTLKSHLNQ HQRIHTGEKP FQCKECGMNF SWSCSLFKHL RSHERTDPIN TLSVEGSLL 839 |
Gene Ontology | GO:0005634; C:nucleus; NAS:UniProtKB. GO:0003677; F:DNA binding; IEA:UniProtKB-KW. GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB. GO:0008270; F:zinc ion binding; NAS:UniProtKB. GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. GO:0016032; P:viral reproduction; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |