| Tag | Content |
|---|
| CPLM ID | CPLM-021364 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Phosphatidylinositol glycan anchor biosynthesis class U protein |
Protein Synonyms/Alias | Cell division cycle protein 91-like 1; Protein CDC91-like 1; GPI transamidase component PIG-U |
Gene Name | PIGU |
Gene Synonyms/Alias | CDC91L1; PSEC0205; UNQ3055/PRO9875 |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 42 | VSPLSSWKRVVEGLS | ubiquitination | [1] | | 91 | KVVFKKQKLLLELDQ | ubiquitination | [1] |
|
Reference | [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization. Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW. Nature. 2013 Apr 18;496(7445):372-6. [ PMID: 23503661] |
Functional Description | Component of the GPI transamidase complex. May be involved in the recognition of either the GPI attachment signal or the lipid portion of GPI. |
Sequence Annotation | REGION 269 289 May be involved in recognition of long- |
Keyword | Alternative splicing; Complete proteome; Direct protein sequencing; Endoplasmic reticulum; GPI-anchor biosynthesis; Membrane; Reference proteome; Transmembrane; Transmembrane helix. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 435 AA |
Protein Sequence | MAAPLVLVLV VAVTVRAALF RSSLAEFISE RVEVVSPLSS WKRVVEGLSL LDLGVSPYSG 60
AVFHEITDAL TAIALYFAIQ DFNKVVFKKQ KLLLELDQYA PDVAELIRTP MEMRYIPLKV 120
ALFYLLNPYT ILSCVAKSTC AINNTLIAFF ILTTIKGSAF LSAIFLALAT YQSLYPLTLF 180
VPGLLYLLQR QYIPVKMKSK AFWIFSWEYA MMYVGSLVVI ICLSFFLLSS WDFIPAVYGF 240
ILSVPDLTPN IGLFWYFFAE MFEHFSLFFV CVFQINVFFY TIPLAIKLKE HPIFFMFIQI 300
AVIAIFKSYP TVGDVALYMA FFPVWNHLYR FLRNIFVLTC IIIVCSLLFP VLWHLWIYAG 360
SANSNFFYAI TLTFNVGQIL LISDYFYAFL RREYYLTHGL YLTAKDGTEA MLVLK 415 |
Gene Ontology | GO:0042765; C:GPI-anchor transamidase complex; IDA:UniProtKB. GO:0005886; C:plasma membrane; IDA:HGNC. GO:0016255; P:attachment of GPI anchor to protein; IMP:UniProtKB. GO:0006501; P:C-terminal protein lipidation; TAS:Reactome. GO:0046425; P:regulation of JAK-STAT cascade; IDA:HGNC. |
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Pfam | |
SMART | |
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PRINTS | |