CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-027947
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 BcDNA.GM09489 
Protein Synonyms/Alias
 Signal recognition particle protein 54k 
Gene Name
 Srp54k 
Gene Synonyms/Alias
 BcDNA.GM09489; CG4659; Dmel_CG4659 
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
85AVFKELVKLVDPGVKacetylation[1]
92KLVDPGVKPYQPIKGacetylation[1]
398DGAKLFSKQPNRCVRacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 508 AA 
Protein Sequence
MVLADLGRKI TTALHSLSKA TVINEEALNS MLKEICAALL EADVNIRLVK QLRENVRAVI 60
DFDEMAGGLN KRRMIQSAVF KELVKLVDPG VKPYQPIKGK ANVVMFVGLQ GSGKTTTCTK 120
LAYHYQKRNW KSCLVCADTF RAGAYDQVKQ NATKARIPFY GSYTEIDPVV IAQDGVDMFK 180
REGFEMIIVD TSGRHKQEES LFEEMLAVSN AVSPDNIIFV MDATIGQACE AQAKAFKDKV 240
DIGSVIITKL DGHAKGGGAL SAVAATQSPI IFIGTGEHID DLEPFKTKPF VSKLLGMGDI 300
EGLIDKVNEL KLDGNDELLE KIKHGHFTIR DMYEQFQNIM KMGPFSQFMN MIPGFSQDFM 360
TKGGEQESMA RVKRMMTMMD SMSDNELDNR DGAKLFSKQP NRCVRVAQGA GVMEREVKEL 420
IAHYTKFSAV VKKMGGVKGL FKQGDMTKNV NPTQMAKLNQ QIAKMIDPRM LQQMGGVGGI 480
QNMMRQLQQG AAGGLGGLGN LMSGFGGK 508 
Gene Ontology
 GO:0005786; C:signal recognition particle, endoplasmic reticulum targeting; ISS:FlyBase.
 GO:0008312; F:7S RNA binding; IEA:InterPro.
 GO:0005525; F:GTP binding; IEA:InterPro.
 GO:0003924; F:GTPase activity; IEA:InterPro.
 GO:0005048; F:signal sequence binding; ISS:FlyBase.
 GO:0006184; P:GTP catabolic process; IEA:GOC.
 GO:0006617; P:SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition; ISS:FlyBase. 
Interpro
 IPR003593; AAA+_ATPase.
 IPR027417; P-loop_NTPase.
 IPR013822; Signal_recog_particl_SRP54_hlx.
 IPR004125; Signal_recog_particle_SRP54_M.
 IPR022941; SRP54.
 IPR006325; SRP54_euk.
 IPR000897; SRP54_GTPase_dom. 
Pfam
 PF00448; SRP54
 PF02881; SRP54_N
 PF02978; SRP_SPB 
SMART
 SM00382; AAA
 SM00962; SRP54
 SM00963; SRP54_N 
PROSITE
 PS00300; SRP54 
PRINTS