CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-011770
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Chitin biosynthesis protein CHS5 
Protein Synonyms/Alias
 Protein CAL3 
Gene Name
 CHS5 
Gene Synonyms/Alias
 CAL3; YLR330W; L8543.18 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
299AEVADENKMPEDTTDubiquitination[1]
584EPSNEDVKPEEKGSEubiquitination[1, 2]
588EDVKPEEKGSEAEDDubiquitination[1]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301]
 [2] Sites of ubiquitin attachment in Saccharomyces cerevisiae.
 Starita LM, Lo RS, Eng JK, von Haller PD, Fields S.
 Proteomics. 2012 Jan;12(2):236-40. [PMID: 22106047] 
Functional Description
 Component of the CHS5/6 complex which mediates export of specific cargo proteins, including chitin synthase CHS3. Also involved in targeting FUS1 to sites of polarized growth. 
Sequence Annotation
 DOMAIN 79 165 Fibronectin type-III.
 DOMAIN 166 262 BRCT.
 MOD_RES 305 305 Phosphothreonine.
 MOD_RES 338 338 Phosphoserine.
 MOD_RES 362 362 Phosphoserine.
 MOD_RES 365 365 Phosphoserine.
 MOD_RES 383 383 Phosphoserine.
 MOD_RES 384 384 Phosphoserine.
 MOD_RES 573 573 Phosphoserine.
 MOD_RES 579 579 Phosphoserine.
 MOD_RES 590 590 Phosphoserine.  
Keyword
 3D-structure; Complete proteome; Golgi apparatus; Membrane; Phosphoprotein; Protein transport; Reference proteome; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 671 AA 
Protein Sequence
MSSVDVLLTV GKLDASLALL TTQDHHVIEF PTVLLPENVK AGSIIKMQVS QNLEEEKKQR 60
NHFKSIQAKI LEKYGTHKPE SPVLKIVNVT QTSCVLAWDP LKLGSAKLKS LILYRKGIRS 120
MVIPNPFKVT TTKISGLSVD TPYEFQLKLI TTSGTLWSEK VILRTHKMTD MSGITVCLGP 180
LDPLKEISDL QISQCLSHIG ARPLQRHVAI DTTHFVCNDL DNEESNEELI RAKHNNIPIV 240
RPEWVRACEV EKRIVGVRGF YLDADQSILK NYTFPPVNEE ELSYSKENEP VAEVADENKM 300
PEDTTDVEQV ASPNDNESNP SEAKEQGEKS GHETAPVSPV EDPLHASTAL ENETTIETVN 360
PSVRSLKSEP VGTPNIEENK ADSSAEAVVE EPNEAVAESS PNEEATGQKS EDTDTHSNEQ 420
ADNGFVQTEE VAENNITTES AGENNEPADD AAMEFGRPEA EIETPEVNES IEDANEPAED 480
SNEPVEDSNK PVKDSNKPVE DSNKPVEDSN KPVEDSNKPV EDANEPVEDT SEPVEDAGEP 540
VQETNEFTTD IASPRHQEED IELEAEPKDA TESVAVEPSN EDVKPEEKGS EAEDDINNVS 600
KEAASGESTT HQKTEASASL ESSAVTEEQE TTEAEVNTDD VLSTKEAKKN TGNSNSNKKK 660
NKKNKKKGKK K 671 
Gene Ontology
 GO:0034044; C:exomer complex; IDA:SGD.
 GO:0043332; C:mating projection tip; IDA:SGD.
 GO:0016020; C:membrane; IEA:UniProtKB-KW.
 GO:0030476; P:ascospore wall assembly; IMP:SGD.
 GO:0006039; P:cell wall chitin catabolic process; IMP:SGD.
 GO:0000282; P:cellular bud site selection; IMP:SGD.
 GO:0000747; P:conjugation with cellular fusion; IMP:SGD.
 GO:0006893; P:Golgi to plasma membrane transport; IMP:SGD.
 GO:0015031; P:protein transport; IEA:UniProtKB-KW.
 GO:0006355; P:regulation of transcription, DNA-dependent; IDA:SGD. 
Interpro
 IPR001357; BRCT_dom.
 IPR003961; Fibronectin_type3.
 IPR013783; Ig-like_fold. 
Pfam
 PF00533; BRCT 
SMART
 SM00292; BRCT
 SM00060; FN3 
PROSITE
 PS50172; BRCT
 PS50853; FN3 
PRINTS