UniProt Accession

 CX7A1_MOUSE; P56392 

Genbank Protein ID

 AA027520; AA444750; AA218039; AF037370; BC060974 

Genbank Nucleotide ID

 AAC23485.1; AAH60974.1 

Protein Name

 Cytochrome c oxidase subunit 7A1, mitochondrial 

Protein Synonyms/Alias

 Cytochrome c oxidase subunit VIIa-heart; Cytochrome c oxidase subunit VIIa-H; Cytochrome c oxidase subunit VIIa-muscle; Cytochrome c oxidase subunit VIIa-M 

Gene Name

 Cox7a1 

Gene Synonyms/Alias

 Cox7a; Cox7ah 

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
31	NRVAEKQKLFQADND	acetylation	[1, 2]
31	NRVAEKQKLFQADND	ubiquitination	[3]

Reference

 [1] The fasted/fed mouse metabolic acetylome: N6-acetylation differences suggest acetylation coordinates organ-specific fuel switching.
 Yang L, Vaitheesvaran B, Hartil K, Robinson AJ, Hoopmann MR, Eng JK, Kurland IJ, Bruce JE.
 J Proteome Res. 2011 Sep 2;10(9):4134-49. [PMID: 21728379]
 [2] Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome.
 Hebert AS, Dittenhafer-Reed KE, Yu W, Bailey DJ, Selen ES, Boersma MD, Carson JJ, Tonelli M, Balloon AJ, Higbee AJ, Westphall MS, Pagliarini DJ, Prolla TA, Assadi-Porter F, Roy S, Denu JM, Coon JJ.
 Mol Cell. 2013 Jan 10;49(1):186-99. [PMID: 23201123]
 [3] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

 This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport. 

Sequence Annotation

  

Keyword

 Complete proteome; Membrane; Mitochondrion; Mitochondrion inner membrane; Reference proteome; Transit peptide; Transmembrane; Transmembrane helix. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 80 AA 

Protein Sequence

Gene Ontology

 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005746; C:mitochondrial respiratory chain; IEA:InterPro.
 GO:0005739; C:mitochondrion; IDA:MGI.
 GO:0004129; F:cytochrome-c oxidase activity; ISS:UniProtKB.
 GO:0009055; F:electron carrier activity; IEA:InterPro. 

Interpro

 IPR003177; Cyt_c_oxidase_su7a. 

Pfam

 PF02238; COX7a 

SMART

  

PROSITE

  

PRINTS