CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-036245
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein transport protein Sec31A 
Protein Synonyms/Alias
  
Gene Name
 SEC31A 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
78KLIWGPYKMDSKGDVubiquitination[1]
206RKNEPIIKVSDHSNRubiquitination[1]
488FEDDSRGKYLELLGYubiquitination[2]
510KIALALNKVDGANVAubiquitination[2]
647IVESCDLKNWREALAubiquitination[2]
729EKVVILRKAVQLTQAubiquitination[1]
1171SATDPQTKRKLDDASubiquitination[1]
1248VVLTQANKLGV****ubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome; Repeat; WD repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1251 AA 
Protein Sequence
MKLKEVDRTA MQAWSPAQNH PIYLATGTSA QQLDATFSTN ASLEIFELDL SDPSLDMKSC 60
ATFSSSHRYH KLIWGPYKMD SKGDVSGVLI AGGENGNIIL YDPSKIIAGD KEVVIAQNDK 120
HTGPVRALDV NIFQTNLVAS GANESEIYIW DLNNFATPMT PGAKTQPPED ISCIAWNRQV 180
QHILASASPS GRATVWDLRK NEPIIKVSDH SNRMHCSGLA WHPDVATQMV LASEDDRLPV 240
IQMWDLRFAS SPLRVLENHA RGILAIAWSM ADPELLLSCG KDAKILCSNP NTGEVLYELP 300
TNTQWCFDIQ WCPRNPAVLS AASFDGRISV YSIMGGSTDG LRQKQVDKLS SSFGNLDPFG 360
TGQPLPPLQI PQQTAQHSIV LPLKKPPKWI RRPVGASFSF GGKLVTFENV RMPSHQGAEQ 420
QQQQHHVFIS QVVTEKEFLS RSDQLQQAVQ SQGFINYCQK KIDASQTEFE KNVWSFLKVN 480
FEDDSRGKYL ELLGYRKEDL GKKIALALNK VDGANVALKD SDQVAQSDGE ESPAAEEQLL 540
GEHIKEEKEE SEFLPSSGGT FNISVSGDID GLITQALLTG NFESAVDLCL HDNRMADAII 600
LAIAGGQELL ARTQKKYFAK SQSKITRLIT AVVMKNWKEI VESCDLKNWR EALAAVLTYA 660
KPDEFSALCD LLGTRLENEG DSLLQTQACL CYICAGNVEK LVACWTKAQD GSHPLSLQDL 720
IEKVVILRKA VQLTQAMDTS TVGVLLAAKM SQYANLLAAQ GSIAAALAFL PDNTNQPNIM 780
QLRDRLCRAQ GEPVAGHESP KIPYEKQQLP KGRPGPVAGH HQMPRVQTQQ YYPHVRIAPT 840
VTTWSNKTPT ALPSHPPAAS PSDTQGENPP PPGFIMHGNV NPNAAGQLPT SPGHMHTQVP 900
PYPQPQPYQP AQPYPFGTGG SAMYRPQQPV APPTSNAYPN TPYISSASSY TGQSQLYAAQ 960
HQASSPTSSP ATSFPPPPSS GASFQHGGPG APPSSSAYAL PPGTTGTLPA ASELPASQRT 1020
GPQNGWNDPP ALNRVPKKKK MPENFMPPVP ITSPIMNPLG DPQSQMLQQQ PSAPVPLSSQ 1080
SSFPQPHLPG GQPFHGVQQP LGQTGMPPSF SKPNIEGAPG APIGNTFQHV QSLPTKKITK 1140
KPIPDEHLIL KTTFEDLIQR CLSSATDPQT KRKLDDASKR LEFLYDKLRE QTLSPTITSG 1200
LHNIARSIET RNYSEGLTMH THIVSTSNFS ETSAFMPVLK VVLTQANKLG V 1251 
Gene Ontology
 GO:0005737; C:cytoplasm; IDA:HPA.
 GO:0043231; C:intracellular membrane-bounded organelle; IDA:HPA. 
Interpro
 IPR015943; WD40/YVTN_repeat-like_dom.
 IPR001680; WD40_repeat.
 IPR017986; WD40_repeat_dom. 
Pfam
 PF00400; WD40 
SMART
 SM00320; WD40 
PROSITE
 PS50082; WD_REPEATS_2
 PS50294; WD_REPEATS_REGION 
PRINTS