UniProt Accession

 PIHD1_HUMAN; Q9NWS0; B4DGN7; B4E2X7; Q9BVL0 

Genbank Protein ID

 AK000650; AK294687; AK304476; BC001108 

Genbank Nucleotide ID

 BAA91307.1; BAG57848.1; BAG65289.1; AAH01108.1 

Protein Name

 PIH1 domain-containing protein 1 

Protein Synonyms/Alias

 Nucleolar protein 17 homolog 

Gene Name

 PIH1D1 

Gene Synonyms/Alias

 NOP17 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
5	***MANPKLLGMGLS	ubiquitination	[1, 2]
153	AREGLEDKYNLQLNP	ubiquitination	[3]
166	NPEWRMMKNRPFMGS	ubiquitination	[3]

Reference

 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789]
 [3] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

  

Sequence Annotation

  

Keyword

 Alternative splicing; Complete proteome; Polymorphism; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 290 AA 

Protein Sequence

Gene Ontology

 GO:0070761; C:pre-snoRNP complex; IDA:BHF-UCL.
 GO:0000492; P:box C/D snoRNP assembly; IMP:BHF-UCL. 

Interpro

 IPR012981; PIH. 

Pfam

 PF08190; PIH1 

SMART

  

PROSITE

  

PRINTS