CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-013234
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Alpha-(1,3)-fucosyltransferase 11 
Protein Synonyms/Alias
 Fucosyltransferase XI; Fuc-TXI; FucT-XI; Galactoside 3-L-fucosyltransferase 11; Fucosyltransferase 11 
Gene Name
 FUT11 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
242IPVDSYGKCLQNRELubiquitination[1, 2]
354YMKYLAYKQPGGITNubiquitination[2]
Reference
 [1] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
 Probable fucosyltransferase (By similarity). 
Sequence Annotation
 CARBOHYD 166 166 N-linked (GlcNAc...) (Potential).
 CARBOHYD 443 443 N-linked (GlcNAc...).
 DISULFID 98 103 By similarity.
 DISULFID 389 392 By similarity.  
Keyword
 Alternative splicing; Complete proteome; Disulfide bond; Glycoprotein; Glycosyltransferase; Golgi apparatus; Membrane; Polymorphism; Reference proteome; Signal-anchor; Transferase; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 492 AA 
Protein Sequence
MAAGPIRVVL VLLGVLSVCA ASGHGSVAER EAGGEAEWAE PWDGAVFRPP SALGAVGVTR 60
SSGTPRPGRE EAGDLPVLLW WSPGLFPHFP GDSERIECAR GACVASRNRR ALRDSRTRAL 120
LFYGTDFRAS AAPLPRLAHQ SWALLHEESP LNNFLLSHGP GIRLFNLTST FSRHSDYPLS 180
LQWLPGTAYL RRPVPPPMER AEWRRRGYAP LLYLQSHCDV PADRDRYVRE LMRHIPVDSY 240
GKCLQNRELP TARLQDTATA TTEDPELLAF LSRYKFHLAL ENAICNDYMT EKLWRPMHLG 300
AVPVYRGSPS VRDWMPNNHS VILIDDFESP QKLAEFIDFL DKNDEEYMKY LAYKQPGGIT 360
NQFLLDSLKH REWGVNDPLL PNYLNGFECF VCDYELARLD AEKAHAASPG DSPVFEPHIA 420
QPSHMDCPVP TPGFGNVEEI PENDSWKEMW LQDYWQGLDQ GEALTAMIHN NETEQTKFWD 480
YLHEIFMKRQ HL 492 
Gene Ontology
 GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell.
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0046920; F:alpha-(1->3)-fucosyltransferase activity; IEA:InterPro.
 GO:0036065; P:fucosylation; IEA:GOC.
 GO:0006486; P:protein glycosylation; IEA:UniProtKB-UniPathway. 
Interpro
 IPR017176; Alpha-1_3-FUT_met.
 IPR001503; Glyco_trans_10. 
Pfam
 PF00852; Glyco_transf_10 
SMART
  
PROSITE
  
PRINTS