CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-043319
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Pyridoxal-dependent decarboxylase domain-containing protein 1 
Protein Synonyms/Alias
  
Gene Name
 PDXDC1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
39AEMGKNLKEAVKMLEubiquitination[1]
43KNLKEAVKMLEDSQRubiquitination[1]
166EEREGLAKICRLAIHubiquitination[1]
270AAVGHTDKIGRLKELubiquitination[1]
353TSNKPTDKLRALPLWubiquitination[1]
376DGFVERIKHACQLSQubiquitination[1]
424PGSDPVFKAVPVPNMubiquitination[1]
569IHAGLLKKLNELESDubiquitination[1]
580LESDLTFKIGPEYKSubiquitination[1]
586FKIGPEYKSMKSCLYubiquitination[1]
633NMTEVVRKGIQEAQVubiquitination[1]
644EAQVELQKASEERLLubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Lyase; Pyridoxal phosphate; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 806 AA 
Protein Sequence
MACSILEGCR REVRRETWKP GPGSEIADPT LAEMGKNLKE AVKMLEDSQR RTEEENGKKL 60
ISGDIPGPLQ GSGQDMVSIL QLVQNLMHGD EDEEPQSPRI QNIGEQGHMA LLGHSLGAYI 120
STLDKEKLRK LTTRILSDTT LWLCRIFRYE NGCAYFHEEE REGLAKICRL AIHSRYEDFV 180
VDGFNVLYNK KPVIYLSAAA RPGLGQYLCN QLGLPFPCLC RVPCNTVFGS QHQMDVAFLE 240
KLIKDDIERG RLPLLLVANA GTAAVGHTDK IGRLKELCEQ YGIWLHVEGV NLATLALGYV 300
SSSVLAAAKC DSMTMTPGPW LGLPAVPAVT LYKHDDPALT LVAGLTSNKP TDKLRALPLW 360
LSLQYLGLDG FVERIKHACQ LSQRLQESLK KVNYIKILVE DELSSPVVVF RFFQELPGSD 420
PVFKAVPVPN MTPSGVGRER HSCDALNRWL GEQLKQLVPA SGLTVMDLEA EGTCLRFSPL 480
MTAAVLGTRG EDVDQLVACI ESKLPVLCCT LQLREEFKQE VEATAGLLYV DDPNWSGIGV 540
VRYEHANDDK SSLKSDPEGE NIHAGLLKKL NELESDLTFK IGPEYKSMKS CLYVGMASDN 600
VDAAELVETI AATAREIEEN SRLLENMTEV VRKGIQEAQV ELQKASEERL LEEGVLRQIP 660
VVGSVLNWFS PVQALQKGRT FNLTAGSLES TEPIYVYKAQ GAGVTLPPTP SGSRTKQRLP 720
GQKPFKRSLR GSDALSETSS VSHIEDLEKV ERLSSGPEQI TLEASSTEGH PGAPSPQHTD 780
QTEAFQKGVP HPEDDHSQVE GPESLR 806 
Gene Ontology
 GO:0016831; F:carboxy-lyase activity; IEA:InterPro.
 GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
 GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro. 
Interpro
 IPR002129; PyrdxlP-dep_de-COase.
 IPR015424; PyrdxlP-dep_Trfase.
 IPR015421; PyrdxlP-dep_Trfase_major_sub1.
 IPR015422; PyrdxlP-dep_Trfase_major_sub2. 
Pfam
 PF00282; Pyridoxal_deC 
SMART
  
PROSITE
  
PRINTS