UniProt Accession

 Q9XTP7_DROME; Q9XTP7 

Genbank Protein ID

 AE014297; AF264033; AY061327; AB028890; AJ243916; AJ243814 

Genbank Nucleotide ID

 AAF54525.1; AAF91395.1; AAL28875.1; BAA94598.1; CAB51032.1; CAB51073.1 

Protein Name

 DOMINA protein 

Protein Synonyms/Alias

 DOMINA protein (WHN-homologue); Jumeau; LD24749p; Winged-helix nude transcription factor; Winged-helix protein jumeaux 

Gene Name

 jumu 

Gene Synonyms/Alias

 Domina; Dwhn; CG4029; Dmel_CG4029 

Created Date

 July 27, 2013 

Organism

 Drosophila melanogaster (Fruit fly) 

NCBI Taxa ID

 7227 

Lysine Modification

Position	Peptide	Type	References
261	NSLEELGKGKGSTLL	acetylation	[1]

Reference

 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; DNA-binding; Nucleus; Reference proteome; Transcription; Transcription regulation. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 719 AA 

Protein Sequence

Gene Ontology

 GO:0000791; C:euchromatin; IDA:FlyBase.
 GO:0005730; C:nucleolus; IDA:FlyBase.
 GO:0005701; C:polytene chromosome chromocenter; IDA:FlyBase.
 GO:0005667; C:transcription factor complex; IBA:RefGenome.
 GO:0008301; F:DNA binding, bending; IBA:RefGenome.
 GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.
 GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
 GO:0008134; F:transcription factor binding; IBA:RefGenome.
 GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IDA:FlyBase.
 GO:0008105; P:asymmetric protein localization; IMP:FlyBase.
 GO:0006325; P:chromatin organization; IMP:FlyBase.
 GO:0048749; P:compound eye development; IMP:FlyBase.
 GO:0050832; P:defense response to fungus; IMP:FlyBase.
 GO:0048813; P:dendrite morphogenesis; IMP:FlyBase.
 GO:0007391; P:dorsal closure; TAS:FlyBase.
 GO:0035050; P:embryonic heart tube development; IMP:FlyBase.
 GO:0007476; P:imaginal disc-derived wing morphogenesis; IMP:FlyBase.
 GO:0007517; P:muscle organ development; IMP:FlyBase.
 GO:0007400; P:neuroblast fate determination; IMP:FlyBase.
 GO:0007000; P:nucleolus organization; IMP:FlyBase.
 GO:0007389; P:pattern specification process; IBA:RefGenome.
 GO:0051302; P:regulation of cell division; IMP:FlyBase.
 GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome. 

Interpro

 IPR001766; TF_fork_head.
 IPR018122; TF_fork_head_CS.
 IPR011991; WHTH_DNA-bd_dom. 

Pfam

 PF00250; Fork_head 

SMART

 SM00339; FH 

PROSITE

 PS00658; FORK_HEAD_2
 PS50039; FORK_HEAD_3 

PRINTS

 PR00053; FORKHEAD.