UniProt Accession

 M0R2S0_HUMAN; M0R2S0 

Genbank Protein ID

 AC011462 

Genbank Nucleotide ID

  

Protein Name

 Transforming growth factor beta-1 

Protein Synonyms/Alias

  

Gene Name

 TGFB1 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
54	YCFSSTEKNCCVRQL	ubiquitination	[1, 2]

Reference

 [1] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Disulfide bond; Growth factor; Reference proteome; Secreted. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 120 AA 

Protein Sequence

Gene Ontology

 GO:0005576; C:extracellular region; IEA:UniProtKB-KW. 

Interpro

 IPR001839; TGF-b_C.
 IPR015615; TGF-beta-rel.
 IPR017948; TGFb_CS. 

Pfam

 PF00019; TGF_beta 

SMART

 SM00204; TGFB 

PROSITE

 PS00250; TGF_BETA_1
 PS51362; TGF_BETA_2 

PRINTS