| Tag | Content |
|---|
| CPLM ID | CPLM-013575 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | IQ motif and SEC7 domain-containing protein 2 |
Protein Synonyms/Alias | |
Gene Name | Iqsec2 |
Gene Synonyms/Alias | Kiaa0522 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 903 | MKLDDFIKNLRGVDN | ubiquitination | [1] | | 1126 | YGAGDGLKRGALSSS | ubiquitination | [1] |
|
Reference | [1] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis. Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J. J Proteome Res. 2012 Sep 7;11(9):4722-32. [ PMID: 22871113] |
Functional Description | |
Sequence Annotation | DOMAIN 337 366 IQ.
DOMAIN 736 929 SEC7.
DOMAIN 941 1075 PH.
MOD_RES 82 82 Phosphoserine.
MOD_RES 89 89 Phosphotyrosine.
MOD_RES 383 383 Phosphoserine.
MOD_RES 402 402 Phosphoserine.
MOD_RES 611 611 Phosphotyrosine.
MOD_RES 923 923 Phosphotyrosine.
MOD_RES 1119 1119 Phosphotyrosine. |
Keyword | Coiled coil; Complete proteome; Cytoplasm; Phosphoprotein; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 1478 AA |
Protein Sequence | MEAGSGPPGG PGSESPNRAV EYLLELNNII ESQQQLLETQ RRRIEELEGQ LDQLTQENRD 60
LREESQLHRG ELHRDPLGAR DSPGRESQYQ NLRETQFHHR ELRESQFHQA SRDVGYPNRD 120
GAYQNREAIY RDKEREASYQ LQDTTGYTAR ERDVAQCHLH HENPALGRER GGREAGPAHP 180
GREKEAGYSA AVGVGQRPPR ERGQLSRGAS RSSSPGAGGG HSTSTSTSPA TTLQRNVEGD 240
APGSDLSTAV DSPGSQPPYR LSQLPPTSSH MGGPPAGVGL PWAQRARLQP ASVALRKQEE 300
EEIKRSKALS DSYELSTDLQ DKKVEMLERK YGGSFLSRRA ARTIQTAFRQ YRMNKNFERL 360
RSSASESRMS RRIILSNMRM QFSFEEYEKA QNPAYFEGKP ASLDEGAMAG ARSHRLERGL 420
PYGGSCGGGI DGGGSSVTTS GEFSNDITEL EDSFSKQVKS LAESIDEALN CHPSGPMSEE 480
PGSAQLEKRE SKEQQEDSSA TSFSDLPLYL DDPVPPPSPE RLPSTEPPPQ GRPEFWAPAP 540
LPPVPPPMPP GTREDGSREE GTRRGPGCLE CRDFRLRAAH LPLLTIEPPS DSSVDLSDRS 600
DRGSVHRQLV YEADGCSPHG TLKHKGPPGR APIPHRHYPA PEGPAPAPPG PLPPAPNSGT 660
GPSGVAGGRR LGKCEAAGEN SDGGDNESLE SSSNSNETIN CSSGSSSRDS LREPPATGLC 720
KQTYQRETRH SWDSPAFNND VVQRRHYRIG LNLFNKKPEK GIQYLIERGF LSDTPVGVAH 780
FILERKGLSR QMIGEFLGNR QKQFNRDVLD CVVDEMDFSS MDLDDALRKF QSHIRVQGEA 840
QKVERLIEAF SQRYCVCNPA LVRQFRNPDT IFILAFAIIL LNTDMYSPSV KAERKMKLDD 900
FIKNLRGVDN GEDIPRDLLV GIYQRIQGRE LRTNDDHVSQ VQAVERMIVG KKPVLSLPHR 960
RLVCCCQLYE VPDPNRPQRL GLHQREVFLF NDLLVVTKIF QKKKILVTYS FRQSFPLVEM 1020
HMQLFQNSYY QFGIKLLSAV PGGERKVLII FNAPSLQDRL RFTSDLRESI AEVQEMEKYR 1080
VESELEKQKG MMRPNASQPG GAKDSVNGTL ARSSLEDTYG AGDGLKRGAL SSSLRDLSDA 1140
GKRGRRNSVG SLDSTIEGSV ISSPRPHQRM PPPPPPPPPE EYKSQRPVSN SSSFLGSLFG 1200
SKRGKGPFQM PPPPTGQASA SSSSASSTHH HHHHHHHGHS HGGLGVLPDG QSKLQALHAQ 1260
YCQGPGPAPP PYLPPQQPPL PPPPQQPPPL PQLGSIPPPP ASAPPVGPHR HFHAHGPVPG 1320
PQHYTLGRPG RAPRRGAGGH PQFAPHGRHP LHQPTSPLPL YSPAPQHPPA HKQGPKHFIF 1380
SHHPQMMPAA GAAGGPGSRP PGGSYSHPHH PQSPLSPHSP IPPHPSYPPL PPPSPHTPHS 1440
PLPPTSPHGP LHASGPPGTA NPPSANPKAK PSRISTVV 1478 |
Gene Ontology | GO:0030054; C:cell junction; IBA:RefGenome. GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. GO:0005634; C:nucleus; IBA:RefGenome. GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome. GO:0005543; F:phospholipid binding; IEA:InterPro. GO:0030036; P:actin cytoskeleton organization; IBA:RefGenome. GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |