| Tag | Content |
|---|
| CPLM ID | CPLM-003395 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Octaprenyl-diphosphate synthase |
Protein Synonyms/Alias | All-trans-octaprenyl-diphosphate synthase; Octaprenyl pyrophosphate synthase; OPP synthase |
Gene Name | ispB |
Gene Synonyms/Alias | cel; yhbD; b3187; JW3154 |
Created Date | July 27, 2013 |
Organism | Escherichia coli (strain K12) |
NCBI Taxa ID | 83333 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 294 | RAEEEADKAIAALQV | acetylation | [1] |
|
Reference | [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli. Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C. Mol Cell. 2013 Jul 25;51(2):265-72. [ PMID: 23830618] |
Functional Description | Supplies octaprenyl diphosphate, the precursor for the side chain of the isoprenoid quinones ubiquinone and menaquinone. |
Sequence Annotation | METAL 84 84 Magnesium 1 (By similarity).
METAL 84 84 Magnesium 2 (By similarity).
METAL 88 88 Magnesium 1 (By similarity).
METAL 88 88 Magnesium 2 (By similarity).
METAL 211 211 Magnesium 3 (By similarity).
BINDING 45 45 Isopentenyl diphosphate (By similarity).
BINDING 48 48 Isopentenyl diphosphate (By similarity).
BINDING 77 77 Isopentenyl diphosphate (By similarity).
BINDING 93 93 Polyprenyl diphosphate (By similarity).
BINDING 94 94 Isopentenyl diphosphate (By similarity).
BINDING 170 170 Polyprenyl diphosphate (By similarity).
BINDING 171 171 Polyprenyl diphosphate (By similarity).
BINDING 208 208 Polyprenyl diphosphate (By similarity). |
Keyword | Complete proteome; Isoprene biosynthesis; Magnesium; Metal-binding; Reference proteome; Transferase. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 323 AA |
Protein Sequence | MNLEKINELT AQDMAGVNAA ILEQLNSDVQ LINQLGYYIV SGGGKRIRPM IAVLAARAVG 60
YEGNAHVTIA ALIEFIHTAT LLHDDVVDES DMRRGKATAN AAFGNAASVL VGDFIYTRAF 120
QMMTSLGSLK VLEVMSEAVN VIAEGEVLQL MNVNDPDITE ENYMRVIYSK TARLFEAAAQ 180
CSGILAGCTP EEEKGLQDYG RYLGTAFQLI DDLLDYNADG EQLGKNVGDD LNEGKPTLPL 240
LHAMHHGTPE QAQMIRTAIE QGNGRHLLEP VLEAMNACGS LEWTRQRAEE EADKAIAALQ 300
VLPDTPWREA LIGLAHIAVQ RDR 323 |
Gene Ontology | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. GO:0004659; F:prenyltransferase activity; IDA:EcoCyc. GO:0016094; P:polyprenol biosynthetic process; IMP:EcoCyc. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |