CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-040789
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 ATP-binding cassette sub-family D member 4 
Protein Synonyms/Alias
  
Gene Name
 ABCD4 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
375EQVIYPLKEVYPDSGubiquitination[1, 2]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 488 AA 
Protein Sequence
MLIVLNSTLK SFDQFTCNLL YVSWRKDLTE HLHRLYFRGR AYYTLNVLRD DIDNPDQRIS 60
QDVERFCRQL SSMASKLIIS PFTLVYYTYQ CFQSTGWLGP VSIFGYFILG TVVNKTLMGP 120
IVMKLVHQEK LEGDFRAGHV EHMRTDRRLQ RLLQTQRELM SKELWLYIGI NTFDYLGSIL 180
SYVVIAIPIF SGVYGDLSPA ELSTLVSKNA FVCIYLISCF TQLIDLSTTL SDVAGYTHRI 240
GQLRETLLDM SLKSQDCEIL GESEWGLDTP PGWPAAEPAD TAFLLERVSI SAPSSDKPLI 300
KDLSLKISEG QSLLITGNTG TGKTSLLRVL GGLWTSTRGS VQMLTDFGPH GVLFLPQKPF 360
FTDGTLREQV IYPLKEVYPD SGSADDERIL RFLELAGLSN LVARTEGLDQ QVDWNWYDVL 420
SPGEMQRLSF ARLFYLQPKY AVLDEATSAL TEEVESELYR IGQQLGMTFI SVGHRQSLEK 480
VPVLTRMA 488 
Gene Ontology
 GO:0016020; C:membrane; IEA:InterPro.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0016887; F:ATPase activity; IEA:InterPro.
 GO:0006200; P:ATP catabolic process; IEA:GOC.
 GO:0006810; P:transport; IEA:InterPro. 
Interpro
 IPR010509; ABC_Ald_N.
 IPR003439; ABC_transporter-like.
 IPR017871; ABC_transporter_CS.
 IPR027417; P-loop_NTPase. 
Pfam
 PF06472; ABC_membrane_2
 PF00005; ABC_tran 
SMART
  
PROSITE
 PS00211; ABC_TRANSPORTER_1
 PS50893; ABC_TRANSPORTER_2 
PRINTS