UniProt Accession

 RBBP9_RAT; O88350; Q3T1H7 

Genbank Protein ID

 AF025819; BC101915 

Genbank Nucleotide ID

 AAC40205.2; AAI01916.1 

Protein Name

 Putative hydrolase RBBP9 

Protein Synonyms/Alias

 B5T-overexpressed gene protein; Protein BOG; Retinoblastoma-binding protein 9; RBBP-9 

Gene Name

 Rbbp9 

Gene Synonyms/Alias

 Bog 

Created Date

 July 27, 2013 

Organism

 Rattus norvegicus (Rat) 

NCBI Taxa ID

 10116 

Lysine Modification

Position	Peptide	Type	References
156	VADRLDAKLYKFTDR	acetylation	[1]
159	RLDAKLYKFTDRGHF	acetylation	[1]

Reference

 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 

Functional Description

 May play a role in the transformation process due to its capacity to confer resistance to the growth-inhibitory effects of TGF-beta1 through interaction with retinoblastoma and the subsequent displacement of E2F-1. 

Sequence Annotation

 REGION 56 70 Retinoblastoma protein binding
 ACT_SITE 75 75 Charge relay system (Potential).
 ACT_SITE 138 138 Charge relay system (Potential).
 ACT_SITE 165 165 Charge relay system (Potential).
 MOD_RES 49 49 Phosphothreonine; by CK2 (Potential).
 MOD_RES 135 135 Phosphoserine; by CK2 (Potential).  

Keyword

 Complete proteome; Cytoplasm; Hydrolase; Nucleus; Phosphoprotein; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 186 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
 GO:0042127; P:regulation of cell proliferation; IMP:RGD. 

Interpro

 IPR010662; DUF1234_Hydrolase. 

Pfam

 PF06821; Ser_hydrolase 

SMART

  

PROSITE

  

PRINTS