| Tag | Content |
|---|
| CPLM ID | CPLM-002315 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | T-cell surface glycoprotein CD5 |
Protein Synonyms/Alias | Lymphocyte antigen T1/Leu-1; CD5 |
Gene Name | CD5 |
Gene Synonyms/Alias | LEU1 |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 79 | EDPSQASKVCQRLNC | ubiquitination | [1] | | 273 | LCSGFQPKVQSRLVG | ubiquitination | [1] | | 346 | GLFCPHQKLSQCHEL | ubiquitination | [1] |
|
Reference | [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments. Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA. Mol Cell Proteomics. 2013 Mar;12(3):825-31. [ PMID: 23266961] |
Functional Description | May act as a receptor in regulating T-cell proliferation. |
Sequence Annotation | DOMAIN 35 133 SRCR 1.
DOMAIN 159 268 SRCR 2.
DOMAIN 276 368 SRCR 3.
MOD_RES 439 439 Phosphoserine.
MOD_RES 453 453 Phosphotyrosine.
MOD_RES 460 460 Phosphoserine.
MOD_RES 483 483 Phosphoserine.
MOD_RES 485 485 Phosphoserine.
CARBOHYD 116 116 N-linked (GlcNAc...) (Potential).
CARBOHYD 241 241 N-linked (GlcNAc...) (Potential).
DISULFID 44 86
DISULFID 60 125
DISULFID 81 132
DISULFID 107 117
DISULFID 201 267 By similarity.
DISULFID 244 250 By similarity.
DISULFID 285 321
DISULFID 301 360
DISULFID 316 367
DISULFID 342 350 |
Keyword | 3D-structure; Cell membrane; Complete proteome; Disulfide bond; Glycoprotein; Membrane; Phosphoprotein; Polymorphism; Reference proteome; Repeat; Signal; Transmembrane; Transmembrane helix. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 495 AA |
Protein Sequence | MPMGSLQPLA TLYLLGMLVA SCLGRLSWYD PDFQARLTRS NSKCQGQLEV YLKDGWHMVC 60
SQSWGRSSKQ WEDPSQASKV CQRLNCGVPL SLGPFLVTYT PQSSIICYGQ LGSFSNCSHS 120
RNDMCHSLGL TCLEPQKTTP PTTRPPPTTT PEPTAPPRLQ LVAQSGGQHC AGVVEFYSGS 180
LGGTISYEAQ DKTQDLENFL CNNLQCGSFL KHLPETEAGR AQDPGEPREH QPLPIQWKIQ 240
NSSCTSLEHC FRKIKPQKSG RVLALLCSGF QPKVQSRLVG GSSICEGTVE VRQGAQWAAL 300
CDSSSARSSL RWEEVCREQQ CGSVNSYRVL DAGDPTSRGL FCPHQKLSQC HELWERNSYC 360
KKVFVTCQDP NPAGLAAGTV ASIILALVLL VVLLVVCGPL AYKKLVKKFR QKKQRQWIGP 420
TGMNQNMSFH RNHTATVRSH AENPTASHVD NEYSQPPRNS HLSAYPALEG ALHRSSMQPD 480
NSSDSDYDLH GAQRL 495 |
Gene Ontology | GO:0009897; C:external side of plasma membrane; IEA:Compara. GO:0005887; C:integral to plasma membrane; NAS:UniProtKB. GO:0005044; F:scavenger receptor activity; IEA:InterPro. GO:0004888; F:transmembrane signaling receptor activity; NAS:UniProtKB. GO:0008283; P:cell proliferation; NAS:UniProtKB. GO:0008037; P:cell recognition; NAS:UniProtKB. GO:0031295; P:T cell costimulation; IEA:Compara. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |