CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-027588
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 FADD/MORT1 protein with death effector domain 
Protein Synonyms/Alias
 Fas (TNFRSF6)-associated via death domain; Fas death domain associated protein; Protein Fadd 
Gene Name
 Fadd 
Gene Synonyms/Alias
 fadd; rCG_48606 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
125ELKVSEAKIDGIEERacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 208 AA 
Protein Sequence
MDPFLVLLHS LSSSLSGNDL TDLKFLCRER VSKRKLERVQ SGLDLFSVLL EQNDLERGHT 60
GLLRELLASL GRHDLLQRLD DFEAGATTAA TPGEADLRVA FDIVCDNVGR DWKRLARELK 120
VSEAKIDGIE ERYPRSLSDR VRETLRVWKN VEKENASVAG LVKALRACRL NLVADLVEEA 180
LMAQGSVSKS DDTSSALRDS TVSFSETP 208 
Gene Ontology
 GO:0031265; C:CD95 death-inducing signaling complex; IDA:RGD.
 GO:0044297; C:cell body; IDA:RGD.
 GO:0005737; C:cytoplasm; IDA:RGD.
 GO:0045121; C:membrane raft; IDA:RGD.
 GO:0043005; C:neuron projection; IDA:RGD.
 GO:0071260; P:cellular response to mechanical stimulus; IEA:Compara.
 GO:0051607; P:defense response to virus; IEA:Compara.
 GO:0097191; P:extrinsic apoptotic signaling pathway; IEA:Compara.
 GO:0070265; P:necrotic cell death; IEA:Compara.
 GO:0043065; P:positive regulation of apoptotic process; IEA:Compara.
 GO:2001238; P:positive regulation of extrinsic apoptotic signaling pathway; IEA:Compara.
 GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IEA:Compara.
 GO:0032757; P:positive regulation of interleukin-8 production; IEA:Compara.
 GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Compara.
 GO:0032760; P:positive regulation of tumor necrosis factor production; IEA:Compara.
 GO:0060340; P:positive regulation of type I interferon-mediated signaling pathway; IEA:Compara.
 GO:0051291; P:protein heterooligomerization; IPI:RGD. 
Interpro
 IPR011029; DEATH-like_dom.
 IPR000488; Death_domain.
 IPR001875; DED.
 IPR016729; FADD. 
Pfam
 PF00531; Death
 PF01335; DED 
SMART
 SM00005; DEATH
 SM00031; DED 
PROSITE
 PS50017; DEATH_DOMAIN
 PS50168; DED 
PRINTS