| Tag | Content |
|---|
| CPLM ID | CPLM-023741 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Zinc finger and BTB domain-containing protein 12 |
Protein Synonyms/Alias | Protein G10 |
Gene Name | ZBTB12 |
Gene Synonyms/Alias | C6orf46; G10; NG35 |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 134 | IEPKIGLKEDGVSEA | ubiquitination | [1] | | 331 | FSGGNPLKNIKCTKC | ubiquitination | [1] |
|
Reference | [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments. Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA. Mol Cell Proteomics. 2013 Mar;12(3):825-31. [ PMID: 23266961] |
Functional Description | May be involved in transcriptional regulation. |
Sequence Annotation | DOMAIN 33 97 BTB.
ZN_FING 333 356 C2H2-type 1.
ZN_FING 359 381 C2H2-type 2.
ZN_FING 387 409 C2H2-type 3.
ZN_FING 415 438 C2H2-type 4.
MOD_RES 19 19 Phosphothreonine. |
Keyword | Complete proteome; DNA-binding; Metal-binding; Nucleus; Phosphoprotein; Reference proteome; Repeat; Transcription; Transcription regulation; Zinc; Zinc-finger. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 459 AA |
Protein Sequence | MASGVEVLRF QLPGHEAATL RNMNQLRAEE RFCDVTIVAD SLKFRGHKVI LAACSPFLRD 60
QFLLNPSSEL QVSLMHSARI VADLLLSCYT GALEFAVRDI VNYLTAASYL QMEHVVEKCR 120
NALSQFIEPK IGLKEDGVSE ASLVSSISAT KSLLPPARTP KPAPKPPPPP PLPPPLLRPV 180
KLEFPLDEDL ELKAEEEDED EDEDVSDICI VKVESALEVA HRLKPPGGLG GGLGIGGSVG 240
GHLGELAQSS VPPSTVAPPQ GVVKACYSLS EDAEGEGLLL IPGGRASVGA TSGLVEAAAV 300
AMAARGAGGS LGAGGSRGPL PGGFSGGNPL KNIKCTKCPE VFQGVEKLVF HMRAQHFIFM 360
CPRCGKQFNH SSNLNRHMNV HRGVKSHSCG ICGKCFTQKS TLHDHLNLHS GARPYRCSYC 420
DVRFAHKPAI RRHLKEQHGK TTAENVLEAS VAEINVLIR 459 |
Gene Ontology | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. GO:0003677; F:DNA binding; IEA:UniProtKB-KW. GO:0008270; F:zinc ion binding; IEA:InterPro. GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW. GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |