CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-033872
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein Gm3940 
Protein Synonyms/Alias
  
Gene Name
 Gm3940 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
36LKGVHSHKKTLRLRRacetylation[1]
57KSAPRRNKLDHYAIIacetylation[2, 3]
57KSAPRRNKLDHYAIIubiquitination[4]
65LDHYAIIKFPLTTESacetylation[5]
Reference
 [1] Quantification of mitochondrial acetylation dynamics highlights prominent sites of metabolic regulation.
 Still AJ, Floyd BJ, Hebert AS, Bingman CA, Carson JJ, Gunderson DR, Dolan BK, Grimsrud PA, Dittenhafer-Reed KE, Stapleton DS, Keller MP, Westphall MS, Denu JM, Attie AD, Coon JJ, Pagliarini DJ.
 J Biol Chem. 2013 Jul 17;. [PMID: 23864654]
 [2] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377]
 [3] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337]
 [4] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [5] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome; Ribonucleoprotein; Ribosomal protein. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 143 AA 
Protein Sequence
MAPKAKKEAP VPPKAEAKAK ALKAKKAVLK GVHSHKKTLR LRRQPKYPRK SAPRRNKLDH 60
YAIIKFPLTT ESAMKKIEDN NTLVFIVDVK ANKHQIKQAV KKLYDIDVAK VNTLIRPDRE 120
KKAYVRLAPD YDALDVANKI GII 143 
Gene Ontology
 GO:0005840; C:ribosome; IEA:UniProtKB-KW.
 GO:0000166; F:nucleotide binding; IEA:InterPro.
 GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
 GO:0006412; P:translation; IEA:InterPro. 
Interpro
 IPR012677; Nucleotide-bd_a/b_plait.
 IPR019985; Ribosomal_L23.
 IPR012678; Ribosomal_L23/L15e_core_dom.
 IPR001014; Ribosomal_L23/L25_CS.
 IPR005633; Ribosomal_L23/L25_N.
 IPR013025; Ribosomal_L25/23. 
Pfam
 PF00276; Ribosomal_L23
 PF03939; Ribosomal_L23eN 
SMART
  
PROSITE
 PS00050; RIBOSOMAL_L23 
PRINTS