CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-034474
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Interleukin-12 receptor subunit beta-2 
Protein Synonyms/Alias
  
Gene Name
 Il12rb2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
242LHYRIYWKERDSTAQacetylation[1]
Reference
 [1] Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways.
 Rardin MJ, Newman JC, Held JM, Cusack MP, Sorensen DJ, Li B, Schilling B, Mooney SD, Kahn CR, Verdin E, Gibson BW.
 Proc Natl Acad Sci U S A. 2013 Apr 16;110(16):6601-6. [PMID: 23576753] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 540 AA 
Protein Sequence
MEPVGILDIW YMKQDIDYDR QQISLFWKSL NPSEARGKIL HYQVTLQEVT KKTTLQNTTR 60
HTSWTRVIPR TGAWTASVSA ANSKGASAPT HINIVDLCGT GLLAPHQVSA KSENMDNILV 120
TWQPPKKADS AVREYIVEWR ALQPGSITKF PPHWLRIPPD NMSALISENI KPYICYEIRV 180
HALSESQGGC SSIRGDSKHK APVSGPHITA ITEKKERLFI SWTHIPFPEQ RGCILHYRIY 240
WKERDSTAQP ELCEIQYRRS QNSHPISSLQ PRVTYVLWMT AVTAAGESPQ GNEREFCPQG 300
KANWKAFVIS SICIAIITVG TFSIRYFRQK AFTLLSTLKP QWYSRTIPDP ANSTWVKKYP 360
ILEEKIQLPT DNLLMAWPTP EEPEPLIIHE VLYHMIPVVR QPYYFKRGQG FQGYSTSKQD 420
AMYIANPQAT GTLTAETRQL VNLYKVLESR DPDSKLANLT SPLTVTPVNY LPSHEGYLPS 480
NIEDLSPHEA DPTDSFDLEH QHISLSIFAS SSLRPLIFGG ERLTLDRLKM GYDSLMSNEA 540 
Gene Ontology
 GO:0009897; C:external side of plasma membrane; IDA:MGI.
 GO:0004896; F:cytokine receptor activity; IEA:InterPro.
 GO:0019221; P:cytokine-mediated signaling pathway; IEA:GOC.
 GO:0032609; P:interferon-gamma production; IGI:MGI.
 GO:0018108; P:peptidyl-tyrosine phosphorylation; IMP:MGI.
 GO:0032496; P:response to lipopolysaccharide; IGI:MGI. 
Interpro
 IPR003961; Fibronectin_type3.
 IPR003529; Hematopoietin_rcpt_Gp130_CS.
 IPR013783; Ig-like_fold. 
Pfam
 PF00041; fn3 
SMART
 SM00060; FN3 
PROSITE
 PS50853; FN3
 PS01353; HEMATOPO_REC_L_F2 
PRINTS